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Risk of Cardiac Arrhythmias Among Climbers on Mount Everest.
JAMA Cardiol
May 2024
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Importance: Arterial hypoxemia, electrolyte imbalances, and periodic breathing increase the vulnerability to cardiac arrhythmia at altitude.
Objective: To explore the incidence of tachyarrhythmias and bradyarrhythmias in healthy individuals at high altitudes.
Design, Setting, And Participants: This prospective cohort study involved healthy individuals at altitude (8849 m) on Mount Everest, Nepal.
[Clinical characteristics of patients with acute pulmonary embolism in high altitude area of Yunnan province in China].
Zhonghua Xin Xue Guan Bing Za Zhi
January 2022
Clinical Medicine Center and Key Laboratory for Cardiovascular Disease of Yunnan Province, Department of Cardiology, Yan'an Affiliated Hospital, Kunming Medical University, Kunming 650051, China.
To analyze the clinical features of patients with acute pulmonary embolism (APE) living in high altitude area of Yunnan province. This was a cross-sectional retrospective study. APE patients, hospitalized in our hospital between January 2017 and December 2019, were included.
View Article and Find Full Text PDFThe influence of short-term high-altitude acclimatization on cerebral and leg tissue oxygenation post-orthostasis.
Eur J Appl Physiol
November 2021
School of Sport, Health and Exercise Sciences, Bangor University, Bangor, UK.
Purpose: Orthostasis at sea level decreases brain tissue oxygenation and increases risk of syncope. High altitude reduces brain and peripheral muscle tissue oxygenation. This study determined the effect of short-term altitude acclimatization on cerebral and peripheral leg tissue oxygenation index (TOI) post-orthostasis.
View Article and Find Full Text PDFAcute hypoxia in a simulated high-altitude airdrop scenario due to oxygen system failure.
J Appl Physiol (1985)
December 2017
Norwegian Defence Medical Services, Institute of Aviation Medicine, Oslo, Norway.
High-Altitude High Opening (HAHO) is a military operational procedure in which parachute jumps are performed at high altitude requiring supplemental oxygen, putting personnel at risk of acute hypoxia in the event of oxygen equipment failure. This study was initiated by the Norwegian Army to evaluate potential outcomes during failure of oxygen supply, and to explore physiology during acute severe hypobaric hypoxia. A simulated HAHO without supplemental oxygen was carried out in a hypobaric chamber with decompression to 30,000 ft (9,144 m) and then recompression to ground level with a descent rate of 1,000 ft/min (305 m/min).
View Article and Find Full Text PDFPainless acute myocardial infarction on Mount Kilimanjaro.
BMJ Case Rep
March 2016
The Aga Khan Hospital, Dar es Salaam, United Republic of Tanzania.
An individual experiencing dyspnoea or syncope at high altitude is commonly diagnosed to have high-altitude pulmonary edema or cerebral edema. Acute myocardial infarction (AMI) is generally not considered in the differential diagnosis. There have been very rare cases of AMI reported only from Mount Everest.
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