Human antithrombin III has been crystallized from 18 to 21% (w/v) polyethylene glycol 4000 at pH 7.15. The spacegroup is P2(1) with cell parameters a = 89.8 A, b = 100.8 A, c = 70.0 A and beta = 106 degrees. The diffraction limit is 3.2 A. The asymmetric unit contains two protein molecules. Analysis of dissolved crystals for biological activity and by gel electrophoresis suggests that one protein molecule in the asymmetric unit is intact, while the other is cleaved.
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Department of Thoracic Surgery, Baoding First Central Hospital, Baoding, 071000, China.
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J Cardiothorac Surg
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Division of Clinical Medicine, University of Sheffield, Sheffield, UK.
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View Article and Find Full Text PDFIntegrating biomarkers for hemostatic disorders into computational models of blood clot formation: A systematic review.
Math Biosci Eng
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