Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC310083PMC
http://dx.doi.org/10.1093/nar/21.18.4397DOI Listing

Publication Analysis

Top Keywords

tsp45i thermostable
4
thermostable site-specific
4
site-specific endonuclease
4
endonuclease cleaves
4
cleaves recognition
4
recognition sequence
4
sequence 5'-decreases
4
5'-decreases gtsac-3'
4
tsp45i
1
site-specific
1

Similar Publications

The ability to generate null mutants is essential for studying gene function. Gene knockouts in Caenorhabditis elegans can be generated in a high throughput manner using chemical mutagenesis followed by polymerase chain reaction (PCR) assays to detect deletions in a gene of interest. However, current methods for identifying deletions are time and labor intensive and are unable to efficiently detect small deletions.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!