Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC310083 | PMC |
http://dx.doi.org/10.1093/nar/21.18.4397 | DOI Listing |
Mol Biotechnol
January 2006
Department of Biological Chemistry, Johns Hopkins University, Baltimore, MD, USA.
The ability to generate null mutants is essential for studying gene function. Gene knockouts in Caenorhabditis elegans can be generated in a high throughput manner using chemical mutagenesis followed by polymerase chain reaction (PCR) assays to detect deletions in a gene of interest. However, current methods for identifying deletions are time and labor intensive and are unable to efficiently detect small deletions.
View Article and Find Full Text PDFNucleic Acids Res
September 1993
Division of Biotechnology, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, UK.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!