Taenia crassiceps larvae, typically found in rodents, were recovered from fluctuant subcutaneous cystic lesions in a dog. Differential diagnosis included Taenia crassiceps cysticercosis, other metacestode infections, and pseudotumoral skin diseases.
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Int J Parasitol Parasites Wildl
April 2025
Institute of Parasitology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3012, Bern, Switzerland.
Eurasian wolves () and domestic dogs () are definitive hosts of numerous cestode species. While infections with adult stages in canids are usually subclinical, some species pose a zoonotic risk or cause infections in wildlife and livestock, resulting in disease and/or economic losses. This study aimed to determine the prevalence, species composition, and geographical distribution of cestode infections in dogs and free-ranging wolves in Switzerland.
View Article and Find Full Text PDFBrain Sci
November 2024
Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Coyoacán, Mexico.
Pharm Dev Technol
December 2024
Laboratory of Host-Parasite Relationship Studies, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goias, Brazil.
Purpose: This work aimed to develop fenbendazole nanocrystals to evaluate their effects on the energetic metabolism of cysticerci, following an intracranial inoculation in mice.
Methods: Fenbendazole was nanoformulated by the antisolvent method using poloxamers 188 and 407 as stabilizers. The nanosuspensions were lyophilized without cryoprotectants and the nanocrystals were characterized in terms of particle size, zeta potential, and dissolution performance.
Microorganisms
September 2024
Botucatu Medical School, UNESP-Universidade Estadual Paulista, Botucatu 18618-686, Brazil.
Oxidative stress is associated with several infectious diseases, as well as the severity of inflammatory reactions. The control of inflammation during parasite destruction is a target of neurocysticercosis treatment, as inflammation is strongly related to symptom severity. In this study, we investigated the presence of malondialdehyde and protein carbonyl, two by-products of reactive oxygen species (ROS), in an experimental model of extraparenchymal neurocysticercosis.
View Article and Find Full Text PDFTrop Med Infect Dis
September 2024
Department of Neurosciences and Mental Health, Botucatu Medical School, UNESP-São Paulo State University, Botucatu 18618-686, Brazil.
Background: Experimental models of neurocysticercosis (NCC) are helpful for an improved understanding of the pathophysiological mechanisms of human diseases and for testing novel therapeutic approaches. Controlling inflammation without reducing the effectiveness of anthelmintics is an important challenge in treating neurocysticercosis. This study investigates the effects of currently used drugs (Albendazole and Dexamethasone) in treating murine extraparenchymal NCC.
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