AI Article Synopsis
- A study found that mentally retarded children in a social welfare institute had a higher rate of hyperlipoproteinaemia compared to healthy children, indicating a significant health concern (P < 1%).
- The condition is influenced by various factors, especially complications from oligophrenia, including the use of antiepileptics and neuroleptics, viral infections, and other internal and external influences.
- Early biochemical diagnosis is crucial for genetic counseling, preventing worsening mental retardation, managing medication use, and reducing future cardiovascular disease risks.
Article Abstract
Screening revealed a significantly higher incidence of hyperlipoproteinaemia in mentally retarded children in an Institute for Social Welfare than in the healthy child population (P 1%). In the aetiology participate most markedly secondary influences ensuing in particular from complications of the basic diagnosis of oligophrenia. It is mainly a question of the action of antiepileptics, neuroleptics, the influence of viral hepatic infections and other endogenous and exogenous factors. Early diagnosis of hyperlipoproteinaemia is possible so far only by biochemical methods. It is essential for genetic counselling, for prevention of deterioration as regards mental retardation, restriction of pharmacotherapy and later for a reduced risk of development of cardiovascular disease.
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