This paper examines individual developmental profiles drawn from a series of longitudinal studies of cognitive development and problem-solving in children with Down's syndrome (DS) from birth to 11 years of age. These highlight the difficulties in explaining DS development in terms of a slowed-down version of normal development and illustrate how, from a very early age, developmental progress in DS is undermined by the children's failure to exercise and maintain existing skills and by their counter-productive approach to learning new skills. Developmental instability and inefficient learning were found to characterize performance on contingency detection tasks, on tests of object concept development, and on standardized intelligence tests. Implications of the findings for assessment, educational practice and developmental theory are discussed.
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http://dx.doi.org/10.1111/j.1365-2788.1993.tb00882.x | DOI Listing |
BMC Nurs
January 2025
Department of Nursing, Children's Hospital of Soochow University, No. 92 Zhong Nan Street, Soochow, Jiangsu Province, China.
Background: This study aimed to integrate the experiences of caregivers of children with Down syndrome during the care process and understand their feelings and needs.
Methods: We used Page et al.'s (2021) Preferred Reporting Items for Systematic Reviews and Meta-synthesis Statement.
Front Rehabil Sci
January 2025
iCan Shine, Inc., Miami, FL, United States.
Background: Drowning is a leading cause of death for children. Some populations of children with disabilities, such as children with autism, experience a health disparity in drowning when compared to peers without disabilities.
Objective: This study presents a secondary data analysis of the response to intervention for a 5-day adapted swim instruction program (iCan Swim) for children with disabilities ( = 164 participants) ages 3-18 years.
Am J Med Genet A
January 2025
Down Syndrome Program, Division of Medical Genetics and Metabolism, Department of Pediatrics, Massachusetts General Hospital, Boston, Massachusetts, USA.
Parents of children with Down syndrome have historically reported poor experiences receiving a prenatal diagnosis. In a 2003 survey, mothers reported that their physicians pitied them, emphasized negative aspects of Down syndrome, and encouraged them to terminate the pregnancy. This study assesses whether parents' perceptions have since improved.
View Article and Find Full Text PDFAm J Med Genet A
January 2025
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan, US.
The American Academy of Pediatrics (AAP) health supervision guidelines for children with Down syndrome are important for preventative and symptom-based care. Studies, however, have shown low overall adherence to these care recommendations due to a lack of provider familiarity, inaccessibility of a medical home, and caregiver burden. In a population of children with Down syndrome, using a retrospective chart review, we evaluated overall patient adherence to the medical components of the 2011 AAP guidelines, along with potential influencing factors, to determine if there was a difference in adherence between those who had genetic counseling and those who had not.
View Article and Find Full Text PDFInt J Mol Med
March 2025
Department of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Chongqing 400014, P.R. China.
Sepsis is often a cause of mortality in patients admitted to the intensive care unit. Notably, the heart is the organ most susceptible to the impact of sepsis and this condition is referred to as sepsis‑induced cardiomyopathy (SIC). Low triiodothyronine (T3) syndrome frequently occurs in patients with sepsis, and the heart is one of the most important target organs for the action of T3.
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