Benign and malignant pathology of the vulva.

In this review, we focus on rare benign and malignant diseases. It is shown that benign vulvar conditions require thorough examination of other parts of the body, because a relationship with systemic diseases, like cicatricial pemphigoid, pemphigus vulgaris, toxic epidermal necrolysis, infections with parasites and Behçet's syndrome, may be present. Co-operation with medical specialists is warranted. One in every 10 malignancies of the vulva is not a squamous cell carcinoma. Apart from melanoma, several other tumors can occur on the vulva. A correct histological diagnosis is of paramount importance because treatment strategies depend on it.