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Oral Lipids/Fatty Acids Supplements and Eczema: What Is Known?
Dermatitis
January 2025
Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
The pathogenesis of atopic dermatitis (AD) points to skin barrier dysfunction as a critical piece of the puzzle. Deficiencies in fatty acids and ceramides-key elements of the skin barrier-have been linked to AD. Fatty acids can be separated into omega-3 and omega-6, which can be found in a variety of foods such as fish, nuts, seeds, and even plants.
View Article and Find Full Text PDFCo-encapsulation of borage seed oil and peppermint oil blends within ultrasound-assisted soy protein isolate/purity gum ultra complex nanoparticles: Fabrication, structural interaction mechanisms, and in vitro digestion studies.
Food Chem
January 2025
Teagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, Ireland.
This study aimed at co-encapsulating borage seed oil (BSO)- and peppermint oil (PO) blends in ultrasound-assisted complex nanoparticles stabilized by soy protein isolate (SPI) and purity gum ultra (PGU) in different ratios: SPI/PGU-1:0 (NP), 0:1 (NP), 1:1 (NP), 1:3 (NP), and 3:1 (NP). The BSO- and PO-loaded SPI/PGU complex nanoparticles (BP-loaded SPNPs) coded as NP (SPI-PGU-1:3) revealed a zeta potential of -33.27 mV, a PDI of 0.
View Article and Find Full Text PDF"Sweet space" strategy for solvent system selection in countercurrent chromatography: A case study on separation of polyunsaturated fatty acids from borage oil.
J Sep Sci
June 2024
Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, China.
This study presents a comprehensive strategy for the selection and optimization of solvent systems in countercurrent chromatography (CCC) for the effective separation of compounds. With a focus on traditional organic solvent systems, the research introduces a "sweet space" strategy that merges intuitive understanding with mathematical accuracy, addressing the significant challenges in solvent system selection, a critical bottleneck in the widespread application of CCC. By employing a combination of volume ratios and graphical representations, including both regular and trirectangular tetrahedron models, the proposed approach facilitates a more inclusive and user-friendly strategy for solvent system selection.
View Article and Find Full Text PDFDeflazacort and Nevridol 800 to prevent acute carpal tunnel syndrome in adult distal radius fractures.
Med Glas (Zenica)
February 2024
Department of Orthopaedics and Traumatology, AORN San Pio Hospital, Benevento, Italy.
Aim Acute carpal tunnel syndrome (ACTS) is a well-recognized and common condition following a distal radius fracture. The aim of this study was to test deflazacort associated with Nevridol®800 or deflazacort alone in order to prevent moderate or severe ACTS after the distal radius fracture in adults. Methods Sixty-four patients suffering from extraarticular wrist fractures were divided into three groups.
View Article and Find Full Text PDFBigel Formulations of Nanoencapsulated St. John's Wort Extract-An Approach for Enhanced Wound Healing.
Gels
April 2023
Department of Pharmaceutical Technologies, Faculty of Pharmacy, Medical University of Varna, 9000 Varna, Bulgaria.
This study aimed to develop a semisolid vehicle for topical delivery of nanoencapsulated St. John's wort (SJW) extract, rich in hyperforin (HP), and explore its wound-healing potential. Four nanostructured lipid carriers (NLCs) were obtained: blank and HP-rich SJW extract-loaded (HP-NLC).
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