Human foamy virus polypeptides: identification of env and bel gene products.

J Virol

UPR A0043 CNRS Rétrovirus et Rétrotransposons des Vertébrés, Hôpital Saint-Louis, Paris, France.

Published: June 1993

Human foamy virus (HFV) proteins were identified in human cells cultured in vitro by immunoprecipitation and immunoblotting with specific antisera. Among several viral polypeptides, four glycoproteins of approximately 160, 130, 70, and 48 kDa were identified in HFV-infected cells. gp130 was shown to represent the intracellular env precursor, and gp70 and gp48 were shown to represent the external and transmembrane env proteins, respectively. The nature of gp160, which shares sequences with the env, bel1, and bel2 proteins, is not yet resolved. In addition, a p62 identified with bel1- and bel2-specific antisera likely corresponds to the bet gene product.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC237707PMC
http://dx.doi.org/10.1128/JVI.67.6.3596-3600.1993DOI Listing

Publication Analysis

Top Keywords

human foamy
8
foamy virus
8
virus polypeptides
4
polypeptides identification
4
env
4
identification env
4
env bel
4
bel gene
4
gene products
4
products human
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!