Fibroadenomas occupy the first place, in terms of prevalence, among benign breast disorders in adolescent girls. Juvenile giant fibroadenoma is a special though rare form, which must be recognised in terms of differential diagnosis from virginal hyperplasia in its asymmetrical early form and phylloid tumours, the prognosis of which is different. The authors describe the clinical and pathological features necessary for diagnosis and report the results of breast reconstruction after excision via a lateral radial approach in a 14-year-old adolescent girl.
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PeerJ
January 2025
Rye, NY, United States of America.
is one of the best-known pterosaurs, with well over 100 specimens being held in public collections. Most of these represent juvenile animals, and the adults known are typically around 1 m in wingspan. Here we describe a near complete skeleton, preserved partially in 3D, of an animal with a wingspan of around 1.
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December 2024
Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, China.
, the earliest known ceratopsian, is represented by dozens of specimens of different sizes collected from the Upper Jurassic of the Junggar Basin, northwestern China. Here, we present the first comprehensive study on the bone histology of based on ten specimens varying in size. Four ontogenetic stages are recognized: early juvenile, late juvenile, subadult, and adult.
View Article and Find Full Text PDFAsian J Surg
December 2024
Department of Pathology, The First People's Hospital of Shizuishan, Affiliated to Ningxia Medical University, Shizuishan, 753200, Ningxia, China.
Neurobiol Dis
January 2025
IDDRC, Jane and Terry Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
There is a growing consensus that brain development in Huntington's disease (HD) is abnormal, leading to the idea that HD is not only a neurodegenerative but also a neurodevelopmental disorder. Indeed, structural and functional abnormalities have been observed during brain development in both humans and animal models of HD. However, a concurrent study of cortical and striatal development in a genetic model of HD is still lacking.
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November 2024
Department of Functional Neuroanatomy, Institute of Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany.
Activity has long been considered essential for circuit formation and maintenance. This view has recently been challenged by proper synaptogenesis and only mildly affected synapse maintenance in the absence of synaptic activity in forebrain neurons. Here, we investigated whether synaptic activity is necessary for the development and maintenance of the calyx of Held synapse.
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