Download full-text PDF |
Source |
---|
F1000Res
March 2024
EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK.
Organised data is easy to use but the rapid developments in the field of bioimaging, with improvements in instrumentation, detectors, software and experimental techniques, have resulted in an explosion of the volumes of data being generated, making well-organised data an elusive goal. This guide offers a handful of recommendations for bioimage depositors, analysts and microscope and software developers, whose implementation would contribute towards better organised data in preparation for archival. Based on our experience archiving large image datasets in EMPIAR, the BioImage Archive and BioStudies, we propose a number of strategies that we believe would improve the usability (clarity, orderliness, learnability, navigability, self-documentation, coherence and consistency of identifiers, accessibility, succinctness) of future data depositions more useful to the bioimaging community (data authors and analysts, researchers, clinicians, funders, collaborators, industry partners, hardware/software producers, journals, archive developers as well as interested but non-specialist users of bioimaging data).
View Article and Find Full Text PDFHistochem Cell Biol
September 2023
European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK.
Biological imaging is one of the primary tools by which we understand living systems across scales from atoms to organisms. Rapid advances in imaging technology have increased both the spatial and temporal resolutions at which we examine those systems, as well as enabling visualisation of larger tissue volumes. These advances have huge potential but also generate ever increasing amounts of imaging data that must be stored and analysed.
View Article and Find Full Text PDFMethods Cell Biol
July 2023
European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire, United Kingdom.
Volume electron microscopy (vEM) techniques produce scientifically important datasets which are time and resource intensive to generate (Peddie et al., 2022). Public archival of such datasets, usually described in the literature, provides many benefits to the data depositors, to those making use of research results based on the datasets, and to the vEM community at large, both now and in the future.
View Article and Find Full Text PDFSci Rep
April 2022
Geophysical Electrodynamics Department, Federal Research Center Institute of Applied Physics of the Russian Academy of Sciences, Nizhny Novgorod, Russia, 603950.
A new mechanism of charge transport inside a thundercloud is suggested and numerically investigated. The considered mechanism can be called "relay" because it is provided by a dynamical network of a relatively small amount of continuously decaying and arising conducting plasma formations. It manifests itself in two consecutive modes corresponding to pre-streamer and streamer/leader stages of thundercloud development.
View Article and Find Full Text PDFInt J Mol Sci
March 2022
Institute of Macromolecular Compounds, Russian Academy of Sciences, Bolshoi VO 31, 199004 St. Petersburg, Russia.
The growing number of drug-resistant pathogenic bacteria poses a global threat to human health. For this reason, the search for ways to enhance the antibacterial activity of existing antibiotics is now an urgent medical task. The aim of this study was to develop novel delivery systems for polymyxins to improve their antimicrobial properties against various infections.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!