Participation of complement in nasal polyposis.

Folia Microbiol (Praha)

Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague.

Published: October 1993

No changes in immunoglobulin (IgG, IgM and IgA) and complement components C3 and C4 levels could be observed in patients suffering from both recurrent and acute nasal polyposis. However, in both groups of patients a significant decrease of the alternative pathway of complement activation (up to 80%) was found. In addition, patients suffering from the acute disease showed even decreased classical complement pathway (up to 20%). Examination of complement activation pathways was shown to be advantageous for the follow-up of the course of this disease.

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Source
http://dx.doi.org/10.1007/BF02891698DOI Listing

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