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A nonlinear constituent based viscoelastic model for articular cartilage and analysis of tissue remodeling due to altered glycosaminoglycan-collagen interactions.
J Biomech Eng
October 2009
Department of Mechanical Engineering, California Polytechnic State University, San Luis Obispo, 93407, USA.
A constituent based nonlinear viscoelastic (VE) model was modified from a previous study (Vena, et al., 2006, "A Constituent-Based Model for the Nonlinear Viscoelastic Behavior of Ligaments," J. Biomech.
View Article and Find Full Text PDFDifferential effects of cyclic and static pressure on biochemical and morphological properties of chondrocytes from articular cartilage.
Clin Biomech (Bristol)
February 2007
Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110 016, India.
Background: Mechanical stresses are known to play important role on articular cartilage functions in vivo and also on cartilage explants and chondrocytes monolayer culture. This study examined the differential effect of cyclic and static pressures on chondrocytes cultured in alginate matrix, which is physiologically closer to the in vivo environment of cells in cartilage.
Methods: Goat knee joint articular cartilage chondrocytes cultured in alginate beads were exposed to 1.
The in vitro interaction of proteoglycans with type I collagen is modulated by phosphate.
Arch Biochem Biophys
August 1994
Department of Biology, University of New Mexico, Albuquerque 87131.
Binding of proteoglycans to type I collagen in vitro was assessed using radiolabeled decorin, biglycan, and large proteoglycans and acid-extracted bovine tendon collagen. Decorin, biglycan, and large proteoglycans were all bound to collagen fibrils in phosphate-buffered saline (PBS) containing 3 mM sodium phosphate. Only decorin was bound when the phosphate concentration in PBS was increased to 30 mM.
View Article and Find Full Text PDFGlycosaminoglycan-collagen interactions in vitro in the hydralazine-induced collagen disease-like syndrome.
Acta Biochim Pol
October 1993
Department of Clinical Chemistry, Silesian School of Medicine, Sosnowiec, Poland.
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