Possible antifertility agents belonging to substituted indoles.

Biol Pharm Bull

Department of Chemistry, Gulbarga University, India.

Published: January 1993

Of the 21 compounds evaluated for antiimplantation and abortifacient activities, compounds (A1, A2, A4 and B1) and compounds (C1, C2, D1 and D3) were found to exhibit 40% and 30% antiimplantation activity, respectively, in female rats when given orally on days 1-5 postcoitum. The remaining 13 compounds were found to be inactive. All of the 21 compounds were also tested for the abortifacient activity, but all were found to be inactive.

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http://dx.doi.org/10.1248/bpb.16.36DOI Listing

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