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Pressure-controlled inverse ratio ventilation improves gas exchange in obese children undergoing laparoscopic surgery: a randomized controlled study.
Am J Transl Res
November 2023
Department of Anesthesiology, Women and Children's Hospital of Jiaxing Jiaxing 314000, Zhejiang, China.
Background: Obese children undergoing laparoscopic surgery frequently experience high end-tidal carbon dioxide partial pressure (PCO) and respiratory acidosis. This study aimed to investigate the effects of pressure-controlled inverse ratio ventilation (IRV) with an inspiratory to expiratory ratio (I:E) of 1.5:1 on obese children undergoing laparoscopic surgery.
View Article and Find Full Text PDFThe effect of unilateral chest drainage for transpulmonary pressure during mechanical ventilation.
JA Clin Rep
October 2023
Division of Anesthesia and Pain Medicine, Fukushima Medical University Hospital, 1 Hikarigaoka, Fukushima City, Fukushima, Fukushima, 960-1295, Japan.
Introduction: Chest tube drainage is usually performed through an underwater seal at a level of 10-20 cmHO. Based on the definition of transpulmonary pressure, continuous chest drainage creates continuous negative pressure, decreasing pleural surface pressure and increasing transpulmonary pressure. We investigated how unilateral chest drainage could affect the tidal volume or driving pressure during mandatory mechanical ventilation.
View Article and Find Full Text PDFEffects of volume-targeted pressure-controlled inverse ratio ventilation on functional residual capacity and dead space in obese patients undergoing robot-assisted laparoscopic radical prostatectomy.
BJA Open
September 2022
Department of Anaesthesiology, Mizonokuchi Hospital Teikyo University School of Medicine, Kanagawa, Japan.
Background: The effect of inverse inspiration:expiration (I:E) ratio on functional residual capacity (FRC) during pneumoperitoneum is unclear. We hypothesised that volume-targeted pressure-controlled inverse ratio ventilation (vtPC-IRV) would increase FRC by increasing the level of auto-PEEP in low respiratory compliance situations.
Methods: During robot-assisted laparoscopic radical prostatectomy, 20 obese patients were sequentially ventilated with four different settings for 30 min in each setting: (1) control, I:E ratio of 1:2 and baseline airway pressure (BAP) of 5 cm HO; (2) IRV2, I:E ratio of 2:1 and BAP off; (3) IRV3, I:E ratio of 3:1 and BAP off; and (4) IRV4, I:E ratio of 4:1 and BAP off.
Changes in dead space components during pressure-controlled inverse ratio ventilation: A secondary analysis of a randomized trial.
PLoS One
November 2021
Department of Anaesthesiology, Mizonokuchi Hospital Teikyo University School of Medicine, Kanagawa, Japan.
Background: We previously reported that there were no differences between the lung-protective actions of pressure-controlled inverse ratio ventilation and volume control ventilation based on the changes in serum cytokine levels. Dead space represents a ventilation-perfusion mismatch, and can enable us to understand the heterogeneity and elapsed time changes in ventilation-perfusion mismatch.
Methods: This study was a secondary analysis of a randomized controlled trial of patients who underwent robot-assisted laparoscopic radical prostatectomy.
An integrated lumped-parameter model of the cardiovascular system for the simulation of acute ischemic stroke: description of instantaneous changes in hemodynamics.
Math Biosci Eng
May 2021
Department of Information Engineering, UniversitȤ Politecnica delle Marche, Ancona 60131, Italy.
Acute Ischemic Stroke (AIS) is defined as the acute condition of occlusion of a cerebral artery and is often caused by a Hypertensive Condition (HC). Due to its sudden occurrence, AIS is not observable the right moment it occurs, thus information about instantaneous changes in hemodynamics is limited. This study aimed to propose an integrated Lumped Parameter (LP) model of the cardiovascular system to simulate an AIS and describe instantaneous changes in hemodynamics.
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