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J Pineal Res
August 2005
Department of Electron Microscopy, Polish Mother's Memorial Hospital-Research Institute, Medical University of Lodz, Lodz, Poland.
Although there is an increasing evidence that the pineal gland may play a role in human malignancy, the studies on melatonin concentrations in different types of malignant tumors brought about controversial results. However, changes in melatonin concentrations have been observed in some types of human malignant tumors. Therefore, we decided to study the circadian melatonin rhythm in patients suffering from cervical cancer in different stages of progression and to compare them with those in subjects free from neoplastic disease.
View Article and Find Full Text PDFBiomed Pharmacother
October 2003
Halberg Chronobiology Center, University of Minnesota, MMC 8609, 420 Delaware Street SE, Minneapolis, MN 55455, USA.
Psychological procedures, such as self-hypnosis in the form of autogenic training, have been proposed for correcting a deviant, e.g., high blood pressure (BP).
View Article and Find Full Text PDFBiomed Pharmacother
October 2003
Division of Neurocardiology and Chronoecology, Department of Medicine, Tokyo Women's Medical University, Daini Hospital, Nishiogu 2-1-10, Arakawa-ku, Tokyo, 116-8567, Japan.
Effects of geomagnetic disturbance on heart rate variability (HRV), the 1/f fractal scaling in particular, are being assessed in adults living at high latitude, where magnetic storms are more frequent and more intense than at lower latitudes. The latter may constitute a signal or a proxy, and possibly a mechanism underlying both undesirable and desirable effects, depending upon circumstances yet to be elucidated. Any circadecadal stage-dependence of morbidity and/or mortality from certain conditions such as myocardial infarctions remains to be studied in both adult and pediatric populations.
View Article and Find Full Text PDFSteroids
April 2000
Department of Biochemistry, Faculté de Médecine Pitié-Salpêtrière, 91, boulevard de l'Hôpital, 75013, Paris, France.
The effects of 10(-6) and 10(-9) M of progesterone were documented on isoproterenol-stimulated melatonin release by perifused pineal glands removed from female rats in diestrous at two different times of a 12 : 12 h light/dark cycle, 7 and 19 h after light onset (which corresponds to daytime and nighttime, respectively), to look for the existence of a circadian stage-dependence of the hormone effects. Three weeks before the experiment, the rats were synchronized with a 12 : 12 lighting regimen. Progesterone decreased by approximately 50% the release of melatonin during the light span, but not during the dark span.
View Article and Find Full Text PDFSteroids
January 1996
Department of Biochemistry, Faculté de Médecine Pitié-Salpêtrière, Paris, France.
The effects of testosterone (10(-3) M, 10(-6) M, and 10(-9) M) and 17 beta-estradiol (10(-3) M and 10(-9) M) were looked for upon isoproterenol-stimulated melatonin release by perifused pineal glands removed from male rats and female rats in diestrus. Two different times of a 12/12 hour light/dark cycle, i.e.
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