The case of a 65-year-old woman with a calcified lipoma of the interpeduncular fossa presenting with a monoparesis is reported. This was excised, resulting in an improvement of her symptoms. The literature is reviewed.
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Complete third nerve palsy as a presenting feature of an interpeduncular lipoma.
Br J Neurosurg
February 2021
Department of Neurosurgery, University Hospital, Coventry, England.
Background: Intracranial lipomas are rare, benign lesions, of congenital origin commonly found incidentally on imaging studies.
Methods: We describe a case of interpeduncular lipoma in an 18 year-old female presenting with a painful left complete oculomotor (IIIrd) nerve palsy and associated headache, which to the best of our knowledge has not been reported in an adult patient.
Results: Following eye patching and steroid treatment, at 6-week follow-up the patient's pain had significantly improved however the complete IIIrd nerve palsy remained.
The clinical and radiological features of cisternal and pericallosal lipomas.
Acta Neurol Belg
February 2020
Department of Radiology, Medical Faculty, Ataturk University, Kazım Karabekir Mah. Terminal Cad, Yakutiye, Erzurum, Turkey.
Purpose: To demonstrate the clinical and radiological features of pericallosal and cisternal lipomas and to compare these two groups in terms of radiological and clinical features.
Methods: This retrospective study included 23 patients diagnosed with pericallosal and cisternal lipoma between 2010 and 2017. The patients comprised 12 females and 11 males with a mean age of 38.
CMA analysis identifies homozygous deletion of in 2 brothers with primary Microcephaly-1.
Mol Cytogenet
September 2017
Quest Diagnostics Nichols Institute, 33608 Ortega Highway, San Juan Capistrano, CA USA.
Background: Homozygous mutations and deletions of the microcephalin gene (; OMIM *607117) have been identified as a cause of autosomal recessive primary microcephaly and intellectual disability (MIM #251200). Previous studies in families of Asian descent suggest that the severity of the phenotype may vary based on the extent of the genomic alteration. We report chromosome microarray (CMA) findings and the first described family study of a patient with primary microcephaly in a consanguineous Hispanic family.
View Article and Find Full Text PDFAuditory Hallucinosis as a Presenting Feature of Interpeduncular Lipoma with Proximal P1 Segment Fenestration: Report of a Rare Case and Review of Literature on Peduncular Hallucinosis.
J Vasc Interv Neurol
June 2016
Department of Neurological Surgery, Neurological Institute, University Hospitals Case Medical Center, Cleveland, OH, USA.
The authors present a unique case of intracranial lipoma in the interpeduncular cistern associated with proximal P1 segment fenestration. This patient is a 20-year-old male with extensive psychiatric history and complaints of recent auditory hallucinations. Cranial magnetic resonance imaging (MRI) (T1, T2, and FLAIR) showed a hyperintense lesion in the left aspect of interpeduncular cistern with a prominent flow void within the hyperintense lesion suggestive of a combined vascular-lipomatous lesion.
View Article and Find Full Text PDFManaging the patient with oculomotor nerve palsy.
Curr Opin Ophthalmol
September 2013
Pediatric Ophthalmology and Ocular Genetics, Aravind Eye Care System, Madurai, Tamil Nadu, India.
Purpose Of Review: To provide clinically relevant information regarding the evaluation and current treatment options for oculomotor nerve palsies. We survey recent literature and provide some insights into these studies.
Recent Findings: Recent case reports highlight emerging new causes of oculomotor cranial nerve palsies, including sellar chordoma, odontogenic abscess, nonaneurysmal subarachnoid hemorrhage, polycythemia, sphenoiditis, neurobrucellosis, interpeduncular fossa lipoma, metastatic pancreatic cancer, leukemia, and lymphoma.
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