Objective: The effect of bundling and ambient heat on newborn body temperature has not been systematically studied. It was hypothesized that bundling and warm environments can elevate the newborn's temperatures to the range that would prompt clinical concern of neonatal sepsis.
Methods: Twenty well, term newborns more than 1 day old were assigned to the control group (one blanket; 24.0 degrees C room) or the experimental group (five blankets and hat; 26.6 degrees C room). Continuous rectal probe temperatures were monitored over a 2 1/2-hour period.
Results: There were 8 control and 12 experimental newborns. The mean change in rectal temperature after 2 1/2 hours was -0.04 degrees C (SD +/- 0.23) in control newborns and +0.56 degrees C (SD +/- 0.12) in the treatment group (P < .0001, t test). Temperatures in the treatment group rose, after an initial half-hour lag, at a linear rate of 0.27 degrees C per hour without a plateau. Two newborns reached 38.0 degrees C, a rectal temperature that may raise concern of infection.
Conclusions: Bundling and warm environments can elevate newborn body temperature to the "febrile" range in this age group. Physicians treating neonates with elevated temperature should ask about bundling and environmental conditions to differentiate endogenous from exogenous "fevers."
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Front Physiol
January 2025
Human Physiology Research Unit, Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.
Introduction: The fraction of drug circulating in the blood that is not bound to plasma proteins ( ) is considered pharmacologically active since it readily binds to its receptor. evidence suggests that changes in temperature and pH affect the affinity of drug binding to plasma proteins, resulting in changes in . In light of the well-established effects of exercise on body temperature and blood pH, we investigated whether an increase in blood temperature and decrease in pH facilitated through passive heating and exercise translated to a change in the of caffeine.
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January 2025
Department of Ophthalmology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
This study aimed to evaluate ocular surface temperature (OST) in post-COVID-19 patients with different degrees of fever via infrared thermal imaging. There were 16 participants (32 eyes) in the control group, 22 participants (44 eyes) in the moderate and low post-COVID-19 fever group (M & L fever group), and 18 participants (36 eyes) in the high post-COVID-19 fever group (H fever group). All participants underwent an ophthalmic slit lamp examination and ocular thermography.
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January 2025
SANKEN, Osaka University, 8-1 Mihogaoka, Ibaraki, 567-0047, Osaka, Japan.
Hydroxyapatite/zirconia (HAP/ZrO) composites were fabricated via the low-temperature mineralization sintering process (LMSP) at an extremely low temperature of 130 °C to enhance the mechanical properties of HAP and broaden its practical applications. For this purpose, 5-20 vol% calcia-stabilized ZrO were introduced into HAP, and HAP/ZrO nanoparticles, mixed with simulated body fluid, were densified under a uniaxial pressure of 800 MPa at 130 °C. At 10 vol% ZrO, the relative density of the HAP/ZrO composite was determined to be 88.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Department of Trauma Surgery, Chungbuk National University Hospital, Cheongju, Republic of Korea.
Rationale: Hypothermia, defined as a core body temperature below 35°C, is a common and serious complication in severe trauma patients, often worsened by hemorrhage and medical interventions. Dexmedetomidine, an α2-adrenergic agonist used for sedation in intensive care units, has known thermoregulatory effects; however, its association with hypothermia in trauma patients remains insufficiently explored.
Patient Concerns: A 40-year-old male with severe polytrauma from a motor vehicle accident presented in distress, with hypotension, tachycardia, and a baseline temperature of 35.
Mol Metab
January 2025
Department of Human Anatomy and Psychobiology, Faculty of Medicine, University of Murcia, Murcia, Spain; Institute of Biomedical Research of Murcia, Virgen de la Arrixaca University Hospital, Murcia, Spain. Electronic address:
Circadian rhythms of metabolic, hormonal, and behavioral fluctuations and their alterations can impact health. An important gap in knowledge in the field is whether the time of the day of exercise and the age of onset of exercise exert distinct effects at the level of whole-body adipose tissue and body composition. The goal of the present study was to determine how exercise at different times of the day during adolescence impacts the adipose tissue transcriptome and content in a rodent model.
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