The overall antioxidative activity was studied in the rabbit brain homogenate, water-soluble protein and lipid fractions. The antioxidative activity of water-soluble protein fraction made a major contribution to the total activity, while the antioxidative activity estimated by the procedure used was not detected in the lipid fraction. Antioxidant activity both in the brain homogenate and water-soluble protein fraction was similarly altered during craniocerebral trauma and after stimulation of the central nervous system in the injured animals.
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