Colposcopy was initially developed by Professor Hinselmann of Germany and is now a procedure that is recognized the world over. Twenty-two countries now represent the International Federation for Cervical Pathology and Colposcopy. Additionally, individual societies representing several countries exist.
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A multimodal deep learning model for cervical pre-cancers and cancers prediction: Development and internal validation study.
Comput Biol Med
January 2025
Institute of the Cervix, Paris, France. Electronic address:
Background: The current cervical cancer screening and diagnosis have limitations due to their subjectivity and lack of reproducibility. We describe the development of a deep learning (DL)-based diagnostic risk prediction model and evaluate its potential for clinical impact.
Method: We developed and internally validated a DL model which accommodates both clinical data and colposcopy images in predicting the patients CIN2+ status using a retrospective cohort of 6356 cases of LEEP-conization/cone-biopsy (gold-standard diagnosis) following an abnormal screening result.
Reproductive Health Among School Employees in Vijayapura, Karnataka.
Cureus
December 2024
Obstetrics and Gynecology, Shri B M Patil Medical College Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, IND.
Background Cervical cancer typically progresses over 10-20 years, making it a preventable disease and underscoring the importance of screening. In low-resource settings, Papanicolaou (Pap) smears and visual inspection with acetic acid (VIA) serve as primary screening tools. This study was conducted as part of the noncommunicable disease camps organized by the government of Karnataka, India.
View Article and Find Full Text PDFThe value of endocervical curettage for diagnosis of cervical precancers or worse at colposcopy of women with atypical glandular cells cytology.
Front Med (Lausanne)
December 2024
Department of Pathology, Fujian Maternity and Child Health Hospital College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Objective: This study evaluates the effectiveness of endocervical curettage (ECC) in identifying additional cervical cancer and its precursors in women with atypical glandular cells (AGC) cytology.
Methods: We conducted a retrospective analysis of medical records for women referred to colposcopy with AGC cytology between January 2019 and December 2023. The study included 433 women with AGC cytology who underwent both biopsy and ECC.
The variations in the natural history of high-risk human papillomavirus infections in Chinese healthy women aged 27-45 years compared with 18-26 years: A prospective cohort study.
Int J Cancer
March 2025
State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health, Xiamen University, Xiamen, Fujian Province, China.
Article Synopsis
- The study followed 3,681 healthy women aged 18-45 for over 5 years to investigate HR-HPV infections and their outcomes, using regular cervical testing and colposcopy for abnormal results.
- Data indicated that younger women (18-26 years) had a higher incidence of persistent HR-HPV infections and cervical lesions (CIN2+) than mid-adult women (27-45 years), suggesting age-related differences in risk.
- Despite lower rates of infection and lesions in mid-adult women, they still face a significant risk of acquiring HR-HPV infections that could lead to cervical issues, highlighting the need for continued monitoring.
High Risk of HPV Related Preneoplastic and Neoplastic Vulvar Lesions in Women Living With HIV.
J Low Genit Tract Dis
December 2024
Neurosurgical Intensive Care Unit, Department of Neuroscience, San Carlo Borromeo Hospital, ASST Santi Paolo e Carlo, Milan, Italy.
Objective: We aimed to investigate the epidemiology of human papilloma virus (HPV)-related preneoplastic and neoplastic vulvar lesions in a large cohort of women living with HIV (WLWH).
Materials And Methods: We retrospectively selected 1,796 WLWH who had a gynecological examination, cervical cytology, high-risk (HR-) HPV test, vulvoscopy, and colposcopy with targeted biopsies when necessary between 1987 and 2020 at 2 Italian institutions. Univariable and multivariable regression analyses were carried out to test the association of the anamnestic and clinical data with the development of precancerous and cancerous lesions.
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