In unanesthetized immobilized cats, under repeated administration of small doses of nembutal (2-3 mg/kg), connections between the projection and the parietal associatition cortical areas was studied as well as the interaction between spindles elicited by stimulation of these areas. Stimulation of the primary sensory areas (auditory or somatosensory) was shown to be able to elicit spindles not only in the stimulated area but in the association cortex too. This latter spindle, being kind of induced from the sensory areas, interacts with the spindles elicited by the direct electrical stimulation on the association cortex.
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Adv Pharm Bull
October 2024
Cancer Chemoprevention Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Sleman, Yogyakarta, Indonesia.
Purpose: The HLF and HuH-6 cell lines represent hepatocellular carcinoma (HCC) with different characteristics in chromosome content that may give different drug responses. Here, PGV-1 was intended to challenge the growth-suppressing effect on HLF and HuH-6 and trace the molecular target mechanism of action compared to sorafenib.
Methods: We applied MTT cytotoxic assay, colony forming assay, flow cytometry analysis, immunofluorescence assay and western blot assay.
Int J Mol Sci
October 2024
Museum and Institute of Zoology, Polish Academy of Sciences, ul. Twarda 51/55, 00-818 Warszawa, Poland.
Adv Sci (Weinh)
November 2024
School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Eur J Appl Physiol
October 2024
School of Medical and Health Sciences, Centre for Human Performance, Edith Cowan University, Joondalup, Australia.
Purpose: We compared voluntary drive and corticospinal responses during eccentric (ECC), isometric (ISOM) and concentric (CON) muscle contractions to shed light on neurophysiological mechanisms underpinning the lower voluntary drive in a greater force production in ECC than other contractions.
Methods: Sixteen participants (20-33 years) performed ISOM and isokinetic (30°/s) CON and ECC knee extensor contractions (110°-40° knee flexion) in which electromyographic activity (EMG) was recorded from vastus lateralis. Voluntary activation (VA) was measured during ISOM, CON and ECC maximal voluntary contractions (MVCs).
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