Over a period of 16 months acute mycoplasma pneumonia was diagnosed in 20 patients. All were rapidly and completely cured by ampicillin and cephalosporins, which are ineffective against mycoplasma, indicating that acute mycoplasma infection in children does not require selective treatment, the pneumonia probably being caused by other micro-organisms. There is no prove that mycoplasma pneumonia heals spontaneously, without any therapy.
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http://dx.doi.org/10.1055/s-0028-1104852 | DOI Listing |
Microbiol Spectr
January 2025
Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Unlabelled: This study investigated the impact of the coronavirus disease 2019 (COVID-19) pandemic and its associated restrictive measures on infections in children with acute respiratory tract infection. The study aimed to elucidate the epidemiological characteristics of infections before and during the pandemic and following the easing of restrictive measures. Pharyngeal secretions were collected from 1,0174 pediatric patients with acute respiratory infection (ARI) who were admitted to Shaoxing Maternity and Child Health Care Hospital (Shaoxing, China) between May 2018 and December 2023.
View Article and Find Full Text PDFCase Rep Med
January 2025
Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Relapsing epiglottitis has rarely been reported, and its etiology is not well established. A 44-year-old previously healthy Japanese man presented with a quickly progressing choking sensation. He had been experiencing refractory and relapsing laryngeal edema and probably acute epiglottitis (three episodes within 2 weeks), with rash and elevated pancreatic amylase.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Clinical Laboratory, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Rd, Minhang District, Shanghai, 201102, China.
China has adhered to policies of zero-COVID for almost three years since the outbreak of COVID-19, which has remarkably affected the circulation of respiratory pathogens. However, China has begun to end the zero-COVID policies in late 2022. Here, we reported a resurgence of common respiratory viruses and Mycoplasma pneumoniae with unique epidemiological characteristics among children after ending the zero-COVID policy in Shanghai, China, 2023.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Objective: Mycoplasmas are structurally simple pathogenic microorganisms that can cause a wide range of diseases in humans and animals and conventional antibiotic therapies of fluoroquinolones and tetracyclines are toxic to young children and young animals and macrolide resistance is increasing. In this context, new anti-mycoplasma antimicrobial agents need to be developed. 22-((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxypleuromutilin (compound 16C) is a novel acetamine phenyl pleuromutilin derivative.
View Article and Find Full Text PDFJ Prev Med Hyg
September 2024
Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Acute respiratory infections (ARI) are a leading cause of global morbidity and mortality and they're primarily caused by viruses such as rhinovirus, coronavirus, and respiratory syncytial virus (RSV), and to a lesser extent by bacteria like Streptococcus pneumoniae and Mycoplasma pneumoniae. The study examines the impact of COVID-19 control measures on the circulation of respiratory pathogens, indicating a reduction in infections during the pandemic period. A retrospective study was conducted on 1,286 patients at the "G.
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