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Activin inhibition limits early innate immune response in rat kidney allografts-a pilot study.
Transpl Int
January 2017
Department of Bacteriology and Immunology and Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Activins are members of the transforming growth factor-beta (TGF-β) superfamily of cytokines. They play critical roles in the onset of acute and chronic inflammatory responses. The aim of this study was to investigate how activin inhibition affects acute kidney injury and inflammation after transplantation.
View Article and Find Full Text PDFThe human FCG1 gene encoding the high-affinity Fc gamma RI maps to chromosome 1q21.
Immunogenetics
July 1993
University of Melbourne Department of Medicine, St. Vincent's Hospital, Fitzroy, Vic, Australia.
Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene.
J Immunol
March 1992
Austin Research Institute, Austin Hospital, Heidelberg, Australia.
We describe the isolation and characterization of the gene encoding the mouse high affinity Fc receptor Fc gamma RI. Using a mouse cDNA Fc gamma RI probe four unique overlapping genomic clones were isolated and were found to encode the entire 9 kb of the mouse Fc gamma RI gene. Sequence analysis of the gene showed that six exons account for the entire Fc gamma RI cDNA sequences including the 5'- and 3'-untranslated sequences.
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