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Exploring Dual-Targeted Therapy in the Management of Moderate to Severe Inflammatory Bowel Disease: A Retrospective Study.
Crohns Colitis 360
January 2025
Division of Digestive Diseases and Nutrition, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Background: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), often results in significant morbidity among patients with moderate to severe forms. While biologics and small molecules are effective in inducing remission, many patients experience refractory disease or extraintestinal manifestations. This study assesses the safety and efficacy of dual-targeted therapy in IBD patients treated at the Inflammatory Bowel Disease Center.
View Article and Find Full Text PDFEffective doses received by the gastrointestinal tract compartments of adults due to food intake in Egypt.
Sci Rep
January 2025
Faculty of Computer and Information, South Valley University, Qena, 83523, Egypt.
Ra, Th, and K levels in various foods frequently consumed by Egyptians were determined using a gamma-ray spectrometer based on the germanium detector (HPGe). Activity concentrations of Ra, Th, and K were in the range of < 0.10 to 0.
View Article and Find Full Text PDFImpact of Maxillomandibular Sagittal Variations on Upper Airway Dimensions: A Retrospective Cross-sectional CBCT Evaluation.
J Contemp Dent Pract
October 2024
Department of Oral and Maxillofacial Surgery, College of Dentistry, Ibn Al-Nafis University for Medical Sciences, Sana'a, Yemen, Phone: +86 18682960907, e-mail: Orcid: https://orcid.org/0000-0002-6906-8279.
Aim: This study aimed to analyze the upper airway dimensions in adult patients with different anteroposterior (sagittal) skeletal malocclusions (class I, II, and III) using cone beam computed tomography (CBCT) imaging.
Materials And Methods: This retrospective cross-sectional study involved 90 CBCT records from adult subjects who were categorized into three skeletal groups based on their ANB values: Class I ( = 30), class II ( = 30), and class III ( = 30) and were evaluated. The following upper airway measurements were considered: oropharyngeal airway volume, hypopharyngeal airway volume, pharyngeal airway volume, oropharyngeal airway length, hypopharyngeal airway length, pharyngeal airway length, the most constricted site of the pharyngeal airway, and the most constricted cross-sectional area (MIN-CSA) of the pharyngeal airway.
Multidimensional characterization of craniofacial skeletal phenotype of obstructive sleep apnea in adults.
Eur J Orthod
December 2024
Professor, Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul 02453, Republic of Korea.
Objectives: We aimed to characterize a craniofacial skeletal phenotype (CSP) of adult obstructive sleep apnea (OSA) patients from a multidimensional perspective, exploring the impact of transverse skeletal discrepancy (TSD) on multivariable polysomnographic profiles.
Materials And Methods: This retrospective, cross-sectional study included 102 adult OSA patients. Sagittal, vertical, and transverse skeletal patterns were categorized on the cone beam computed tomography images.
Clinical Characteristics During and After COVID-19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China.
Immun Inflamm Dis
January 2025
Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Background: Revealing the clinical manifestations and associations of COVID-19 before and after negative transition remains an area of significant uncertainty. The aim of this study is to investigate the clinical characteristics observed during and after Omicron infection among a specific population, namely healthcare workers (HCWs).
Methods: From November 4, 2022, to January 15, 2023, HCWs in our hospital were enrolled to document clinical symptoms, prevention, and treatment for COVID-19 using a structured questionnaire.
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