Blood serum was used of 49 rams and 20 ewew infected with Brucell ovis. The study on the total protein and the protein fractions of rams revealed that there existed gamma-globulinemia, the percent of the gamma-globulin rise showing a positive correlation with the morphologic changes in the testes. The alfa-globulins were found to rise immediately following the experimental infecting of the sheep for about a month, after which they came back to normal. In experimental infection the activity of the alkaline phosphatase, aldolase, glutamate-oxalacetate-transaminase, and glutamate-pyruvate-transaminase of the blood serum showed transient characteristic changes, having, however, no diagnostic value.

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