The influence of cerebellectomy in nutritional function was studied in the rat. Feeding behavior and analyses of lipids, proteins, nitrogen, and catecholamines in fecal and urinary excreta and in plasma were studied in 20 cerebellectomized, 20 sham operated, and 20 control animals. The results demonstrate that feeding behavior (quantitative rates of daily absorbed food, body weight, and the choice of the nutriment form) was lower in cerebellectomized animals compared to sham operated and control animals. Rates of steatorrhea and urinary levels of vanylmandelic acid, homovanillic acid, and metanephrine were higher in cerebellectomized animals while plasma levels of proteins, fatty acids, and glycerol were lower. Thus, the cerebellum is involved in nutritional regulation in the rodent.
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http://dx.doi.org/10.1016/0031-9384(93)90325-a | DOI Listing |
Sci Rep
January 2025
Department of Entomology and Plant Pathology, University of Arkansas, Fayetteville, AR, 72701, USA.
Plasma is considered as the fourth state of matter, and atmospheric cold plasma (cold plasma) is a type of plasma consisting of ionized gases containing excited species of atoms, molecules, ions, and free radicals at near room temperature. Cold plasma is generated by applying high voltage to gases, causing it to ionize thus forming plasma. Although cold plasma has been found to break seed dormancy and improve germination rate, only a few studies have explored the potential of cold plasma against insect herbivory.
View Article and Find Full Text PDFJ Chem Ecol
January 2025
Institute of Zoology, University of Regensburg, Universitätsstraße 31, 93053, Regensburg, Germany.
In modern agriculture, control of insect pests is achieved by using insecticides that can also have lethal and sublethal effects on beneficial non-target organisms. Here, we investigate acute toxicity and sublethal effects of four insecticides on the males' sex pheromone response and the female host finding ability of the Drosophila parasitoid Leptopilina heterotoma. The nicotinic acetylcholine receptor antagonists acetamiprid, flupyradifurone and sulfoxaflor, as well as the acetylcholinesterase inhibitor dimethoate were applied topically as acetone solutions.
View Article and Find Full Text PDFSci Rep
January 2025
Division of Human Nutrition and Health, Wageningen University, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Cannabidiol (CBD), a specialized metabolite (phytocannabinoid) abundant in Cannabis sativa, is attracting increasing attention for its alleged health-promoting properties. The present study aimed to investigate the pharmacokinetics of CBD and its primary metabolite, 7-hydroxy-cannabidiol (7-OH-CBD), following a single oral dose of a CBD-rich Cannabis sativa extract, equivalent to 70 mg CBD, in healthy male (n=5) and female (n=6) participants. Using a randomized crossover design, the study evaluated the impact of a standardized high-fat meal compared to fasting on the oral bioavailability of CBD.
View Article and Find Full Text PDFInt J Pharm
January 2025
Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Ghent, Belgium. Electronic address:
In recent years, continuous manufacturing (CM) has become increasingly popular in the pharmaceutical industry for the production of oral solid dosage (OSD) forms. Most of the newly developed active pharmaceutical ingredients (APIs) nowadays are extremely cohesive and sticky with a mean particle size particle of <100μm, a wide particle size distribution (PSD) and a high tendency to agglomerate, making them difficult to accurately dose using loss-in-weight equipment during CM. In this research paper, the effect of various glidants on the volumetric and gravimetric feeding of several APIs was assessed.
View Article and Find Full Text PDFAn Acad Bras Cienc
January 2025
Shandong University of Science and Technology, College of Earth Science and Engineering, 579, Qianwangang Road, Huangdao, Qingdao, Shandong Province, 266590, China.
A "comb-dentition", characterized by long, needle-like, and closely-spaced teeth, is found in the ctenochasmatid pterosaurs as an adaptation for filter-feeding. However, little is known about their tooth replacement pattern, hindering our understanding of the development of the filter-feeding apparatus of the clade. Here, we describe the tooth replacement of the pterosaur Forfexopterus from the Jehol Biota based on high-resolution X-ray Computed Tomography (CT) reconstruction.
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