Objective: To characterize responders/nonresponders to 2 nonsteroidal antiinflammatory drugs by a combination of start variables in the treatment of patients with osteoarthritis (OA) of the hip(s)/knee(s).
Methods: Two hundred eight patients participated in a 3-week randomized double blind parallel group trial.
Results: The responder rate to tiaprofenic acid and naproxen was 52 and 59%, respectively. Correctly characterized by use of a combination of 6 baseline variables were 79% of the patients treated with tiaprofenic acid and 81% treated with naproxen.
Conclusion: Both active drugs were found effective compared with placebo in patients with OA, but with different characteristics.
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