Eighty-six patients with ureteral colic were included in a randomised, prospective, double-blind study of the analgesic efficacy and tolerance of ketoprofen versus diclofenac, both administered intramuscularly. There were no significant differences regarding pain-relief or side-effects.
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http://dx.doi.org/10.3109/00365599309180441 | DOI Listing |
Zh Nevrol Psikhiatr Im S S Korsakova
December 2024
Clinical Hospital of St. Luka, St. Petersburg, Russia.
Objective: To analyze the efficacy and tolerability of aceclofenac in the treatment of patients with acute non-specific musculoskeletal pain in the lower back (ANBP) compared with other NSAIDs (dexketoprofen, nimesulide and lornoxicam), as well as to assess the impact of NSAIDs therapy on the relative risk of recurrence and chronicity of this pathology.
Material And Methods: The study involved 80 patients (47 women and 33 men), average age 52.6 [47.
PLoS One
December 2024
Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.
BMJ Open
October 2024
Medical Affairs, A Menarini Asia Pacific Holdings Pte Ltd, Singapore.
Objectives: This study aims to determine the usage pattern, effectiveness and safety of oral tramadol 75 mg and dexketoprofen trometamol 25 mg fixed-dose combination (TRAM/DKP FDC) in the short-term treatment of moderate-to-severe acute pain in real-world clinical practice in Asia.
Design: Real-world, prospective, multicentre, observational, phase IV study.
Setting: 13 tertiary-care hospital sites across the Philippines, Thailand, Malaysia and Singapore.
Chem Commun (Camb)
September 2024
Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.
A metal-free strategy has been developed for the α-arylation of carboxylic acids, secondary amides, and esters employing arenes as key reagents. This process entails the Lewis-acid catalyzed reductive Friedel-Crafts alkylation of arenes utilizing α-ketoacids, facilitated by silane in HFIP solvent. The transformation exhibits exceptional functional group tolerance, enabling late-stage functionalization of natural products.
View Article and Find Full Text PDFHeliyon
June 2024
Department of Chemistry & Biochemistry, California State University, Fullerton, 800 N. State College, Fullerton, CA, 92834, United States.
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