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De Novo Hypercalcaemia in a Patient With Chronic Hypoparathyroidism.
Cureus
December 2024
Endocrinology, Mallow General Hospital/University College Cork, Cork, IRL.
Calcium Homeostasis in the human body is regulated by hormones, including parathyroid hormone and vitamin D3. Dysfunction in the form of hypoparathyroidism causes hypocalcaemia. In patients treated for primary hypoparathyroidism with activated vitamin D replacement, iatrogenic hypercalcaemia can occur.
View Article and Find Full Text PDFIntraoral microscopic-assisted sialolithotomy for management of medium-large submandibular sialolithiasis: A refined technique.
World J Otorhinolaryngol Head Neck Surg
December 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Suez University, Suez Royal Private Hospital Alexandria Egypt.
Objectives: Sialendoscopy has become the standard treatment for sialolithiasis; however, larger submandibular calculi may require an incisional technique. This study describes and evaluates an intraoral microscopic-assisted sialolithotomy (IMAS) as a refined submandibular stone extraction technique.
Methods: Retrospective case series of 64 submandibular IMAS procedures operated at a tertiary university center and private hospital from 2015 to 2021 were evaluated.
Correlation between liver volume drainage and clinical success after endoscopic biliary drainage of hilar malignant obstruction.
Clinics (Sao Paulo)
December 2024
Division of Endoscopy, Instituto do Câncer do Estado de São Paulo, São Paulo, SP, Brazil; Department of Gastroenterology of Universidade de São Paulo, São Paulo, SP, Brazil.
Background And Aim: Malignant hilar obstruction usually presents in advanced-stage disease with a poor prognosis. Effective biliary drainage is essential for the beginning of palliative chemotherapy. There is a debate on the amount of liver parenchyma that should be drained to achieve clinical success.
View Article and Find Full Text PDFSarcoid Vasculitis in the Skin: A Clinicopathologic Study of 8 Cases With Various Skin Lesions but the Common Unique Cannonball-like Vessel Destruction by Sarcoid Granulomas.
Am J Surg Pathol
November 2024
Department of Dermatology, Fukushima Medical University, Fukushima.
While the skin is a common target organ for sarcoidosis, cutaneous granulomatous vasculitis is rare among patients with sarcoidosis. Due to the lack of detailed studies on cutaneous sarcoid vasculitis, both dermatologists and pathologists remain unfamiliar with this rare but important vasculitic disorder. We clinicopathologically evaluated eight cases with biopsy-proven cutaneous vasculitis and cutaneous sarcoidosis and analyzed morphologic changes in the process of vasculitis for both small vessels and muscular vessels in detail.
View Article and Find Full Text PDFThe Gray Area of Sarcoidosis and Tuberculosis: A Diagnostic Enigma.
Cureus
October 2024
Respiratory Medicine, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Article Synopsis
- A 29-year-old male patient exhibited symptoms that could point to either tuberculosis (TB) or sarcoidosis, and imaging studies showed abnormal lung findings.
- A biopsy indicated necrotizing granulomatous inflammation, suggesting TB, but his symptoms did not improve with TB treatment, leading to a diagnosis of pulmonary sarcoidosis.
- The patient's condition improved significantly with corticosteroid therapy, demonstrating the need for thorough diagnostic evaluations to differentiate between these two diseases.
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