The authors consider the role of selenium deficiency to be of the utmost importance in the deteriorating health status of the Hungarian population. The pathophysiological processes occurring in selenium deficiency and possibly leading to cardio- and cerebrovascular diseases are discussed in detail. The results of human studies investigating the relationship between vascular diseases and selenium deficiency are summarized. It is concluded that selenium deficiency together with other harmful (prooxidant) effects may be responsible for the poor health status of the Hungarian population and therefore the importance of long term selenium supplementation in the prevention of such diseases is stressed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Spatial distribution and driving factors of soil selenium on the Leizhou Peninsula, southern China.
Environ Geochem Health
January 2025
Institute of Geophysical and Geochemical Exploration, Chinese Academy of Geological Sciences, No. 84, Jinguang Road, Langfang, 065000, China.
Selenium (Se) is an essential element for humans, playing a critical role in the functioning of the immune system. The global prevalence of dietary Se deficiency is a significant public health concern, largely attributed to the low levels of Se present in crops. The sufficient Se in plants and humans is determined by the presence of stable Se sources in the soil.
View Article and Find Full Text PDFSystematic low-grade chronic inflammation and intrinsic mechanisms in polycystic ovary syndrome.
Front Immunol
January 2025
Reproductive Endocrinology and Regulation Laboratory, West China Second University Hospital, Sichuan University, Chengdu, China.
Polycystic ovary syndrome (PCOS) is a prevalent endocrine and metabolic disorder affecting 6-20% of women of childbearing age worldwide. Immune cell imbalance and dysregulation of inflammatory factors can lead to systematic low-grade chronic inflammation (SLCI), which plays a pivotal role in the pathogenesis of PCOS. A significant higher infiltration of immune cells such as macrophages and lymphocytes and pro-inflammatory factors IL-6 and TNF-α has been detected in PCOS organ systems, impacting not only the female reproductive system but also other organs such as the cardiovascular, intestine, liver, thyroid, brain and other organs.
View Article and Find Full Text PDFMicro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity.
Immun Ageing
December 2024
Department of Biomedical Sciences, Institute of Health, Jimma University, Jimma, 378, Oromia, Ethiopia.
Immunosenescence, the slow degradation of immune function over time that is a hallmark and driver of aging, makes older people much more likely to be killed by common infections (such as flu) than young adults, but it also contributes greatly to rates of chronic inflammation in later life. Such micro nutrients are crucial for modulating effective immune responses and their deficiencies have been associated with dysfunctional immunity in the elderly. In this review, we specifically focused on the contribution of major micro nutrients (Vitamins A, D and E, Vitamin C; Zinc and Selenium) as immunomodulators in ageing population especially related to inflame-ageing process including autoimmunity.
View Article and Find Full Text PDFEffects of Trace Elements and Vitamins on the Synthesis of Steroid Hormones in Follicular Granulosa Cells of Yak.
Vet Sci
December 2024
College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu 611130, China.
Yak (), a special breed of cattle on the Qinghai-Tibet Plateau, has low fertility due to nutritional deficiency, especially the trace elements. The steroid hormones estradiol (E2) and progesterone (P4) synthesized by yak follicular granulosa cells (BGCs) are involved in the entire reproductive process. In the present study, we investigated the effects of trace elements and vitamins on yak follicular GCs, including the cellular activity, the synthesis of E2 and P4, and the expression of genes related to steroid hormone synthesis.
View Article and Find Full Text PDFSelenium-Deficient FeSe2/Fe3O4 Electrocatalyst for Nitrate Reduction to Ammonia.
Angew Chem Int Ed Engl
December 2024
Qingdao University of Science and Technology, State Key Laboratory Base of Eco-Chemical Engineering College of Chemical Engineering, Qingdao, CHINA.
Electrocatalytic reduction of NO3- is a green and sustainable method that not only helps to treat industrial pollutants in wastewater, but also produces valuable chemicals. However, the slow dynamics of the proton-coupled electron transfer process results in a high barrier and low conversion efficiency. In this work, the Se-deficient FeSe2/Fe3O4 heterojunction was synthesized, which showed excellent electrochemical performance in 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!