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Background: Type 2 Diabetes Mellitus (T2DM) is a significant public health burden. Emerging evidence links volatile organic compounds (VOCs), such as benzene to endocrine disruption and metabolic dysfunction. However, the effects of chronic environmentally relevant VOC exposures on metabolic health are still emerging.
View Article and Find Full Text PDFAssociation of Occupational Noise Exposure and Extended High-Frequency Hearing Loss in Young Workers With Normal Hearing.
Ear Hear
December 2024
Zhejiang Key Laboratory of Multiomics and Molecular Enzymology, Yangtze Delta Region Institute of Tsinghua University, Zhejiang, China.
Objectives: Studies on the relationship between occupational noise exposure and extended high-frequency (EHF) hearing loss are limited. This study investigated the relationship between occupational noise exposure and EHF hearing loss in workers exposed to noise as measured by sound pressure level, exposure duration, and kurtosis to help provide a basis for early detection and prevention of hearing loss in noise-exposed workers.
Design: A cross-sectional survey was conducted among 602 participants with 472 noise-exposed workers and 130 non-noise-exposed controls.
Use of agrochemicals resulted in anemia and inflammation among farmers in Fako Division, Cameroon.
Drug Chem Toxicol
November 2024
Laboratory for Drugs and Molecular Diagnostics Research (ANDI Centre of Excellence for Onchocerciasis Drug Research), Biotechnology Unit, University of Buea, Buea, Cameroon.
The use of agrochemicals as plant growth regulators, pesticides, and soil fertilizers can result in insults among farmers and other non-targeted organisms. The adverse effects of agrochemicals are of global concern, though limited studies have delineated their toxicity on blood cells and inflammatory parameters in Fako division in Cameroon. This study examined the impact of occupational exposure on haematological and inflammatory parameters among farmers in Fako division.
View Article and Find Full Text PDFOccupational exposure to pesticides affects systemic cytokine profile and correlates with poor clinical prognosis in young women with breast cancer.
Immunopharmacol Immunotoxicol
February 2025
Laboratory of Tumor Biology, State University of West Paraná, UNIOESTE, Francisco Beltrão, Brazil.
Objective: Aging is one of the main risk factors for breast cancer. However, the impact of environmental risk factors, such as pesticide exposure, on the clinical outcomes of patients with breast cancer, depending on disease onset, remains unclear.
Material And Methods: This study analyzed clinicopathological data from 188 women with breast cancer, who were either occupationally or domestically exposed to pesticides, or not exposed, according to their age at disease onset (early onset ≤50 years and late onset >50 years).
Human exposure to chromite mining pollution, the toxicity mechanism and health impact.
Heliyon
November 2024
State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Beijing Normal University, Beijing 100875, China.
Article Synopsis
- Chromium mining generates significant toxic metal waste and air pollutants, posing health risks to workers and local populations due to contaminants like hexavalent chromium in the environment.
- The review emphasizes the need for better environmental protection measures and investigates the health impacts of toxic metal exposure, including mechanisms of cancer development.
- It calls for cross-sectional biomonitoring studies for workers and aims to push for improvements in safety and health regulations within the chromite mining industry worldwide.
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