The efficacy and safety of 6 weeks of treatment with desmopressin tablets at doses of 200 to 400 micrograms.at bedtime were investigated in 33 children with monosymptomatic nocturnal enuresis. During an initial 1 to 2-week dose titration period 22 patients (67%) became either completely dry or showed improvement, 7 (21%) showed no response and 4 (12%) dropped out of therapy. During tablet treatment 17 patients on 400 micrograms.and 5 on 200 micrograms.at bedtime increased the number of weekly dry nights from 2.0 +/- 1.6 (standard deviation) during a 2-week observation period to 5.2 +/- 1.9 (p < 0.001). During a subsequent 2-week period 40 micrograms.intranasal desmopressin showed a similar overall efficacy, with a mean of 5.4 +/- 1.6 dry nights per week. In addition, intranasal treatment was able to increase the number of dry nights in 2 of the 7 nonresponders to tablet treatment.
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Beijing Da Xue Xue Bao Yi Xue Ban
February 2025
Department of Critical Care Medicine, Peking University First Hospital, Beijing 100034, China.
This study reports the diagnosis and treatment of a 26-year-old pregnant woman with severe malnutrition combined with acute pyelonephritis causing sepsis, refractory septic shock and multiple organ failure. A female patient, 26 years old, was admitted to hospital mainly due to "menelipsis for more than 19 weeks, nausea and vomiting for 20 days, fever with fatigue for 3 days". At the end of 19 weeks of intrauterine pregnancy, the patient presented with fever accompanied by urinary tract irritation.
View Article and Find Full Text PDFEur J Ophthalmol
January 2025
Department of Ophthalmology, St.Thomas' Hospital, Lambeth Palace Road, London, SE1 7EH, UK.
Introduction: Dry eye disease (DED) can impact the accuracy of biometry measurements prior to cataract surgery (CS), influence visual performance post-CS, and can be exacerbated by CS. We performed a survey to evaluate the DED practice of clinicians directly caring for CS patients.
Design: Prospective face-to-face survey.
Int J Sport Nutr Exerc Metab
January 2025
Centre for Sport Research, Institute of Physical Activity and Nutrition, Deakin University, Geelong, Australia.
Evening consumption of a whey protein rich in the amino acid tryptophan, alpha-lactalbumin (ALAC), has previously shown to benefit sleep-particularly among poor sleepers. Given trained populations often experience sleep difficulty, this study investigated whether evening supplementation of ALAC would influence sleep outcomes, mood, and next-day cognitive performance within a trained population with sleep difficulties. Nineteen trained participants (females, n = 11) with sleep difficulties (Athlete Sleep Screening Questionnaire: 8.
View Article and Find Full Text PDFSci Rep
January 2025
College of New Energy and Environment, Jilin University, Changchun, 130012, China.
Land use and land cover changes (LULCC) alter local surface attributes, thereby modifying energy balance and material exchanges, ultimately impacting meteorological parameters and air quality. The North China Plain (NCP) has undergone rapid urbanization in recent decades, leading to dramatic changes in land use and land cover. This study utilizes the 2020 land use and land cover data obtained from the MODIS satellite to replace the default 2001 data in the Weather Research and Forecasting-Community Multiscale Air Quality (WRF-CMAQ) model.
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