Objective: Esthesioneuroblastomas are uncommon tumors originating in the olfactory epithelium of the superior nasal cavity. Accurate staging appropriately guides therapy and predicts survival. The MR appearance and pattern of contrast enhancement in these tumors have not been well described. The goals of this article were to analyze the MRI characteristics of esthesioneuroblastoma, including extent of tumor, differentiation from obstructive sinus disease, MR signal, and pattern of contrast enhancement.
Materials And Methods: The MR examinations of six patients with proven advanced esthesioneuroblastoma were reviewed. Standard SE T1- and T2-weighted axial images were obtained [550-600/15-25 and 2,000-2,760/80-90 (TR/TE), respectively], followed by postcontrast axial and coronal T1-weighted sequences in all patients.
Results: Five of the six tumors were centered in the superior nasal cavity and one was centered in the lateral ethmoid air cells. Five tumors extended intracranially. Postobstructive sinus disease was always encountered. As compared to gray matter, the signal on T1-weighted images was either hypo- or isointense. On T2-weighted images, the signal varied from iso- to hyperintensity. Contrast enhancement was intense and of variable uniformity.
Conclusion: Magnetic resonance signal characteristics helped to distinguish obstructive sinus disease from tumor. The MR signal characteristics and pattern of contrast enhancement were nonspecific for esthesioneuroblastoma. Enhanced images, particularly in the coronal plane, were very helpful in identifying intracranial extension.
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http://dx.doi.org/10.1097/00004728-199401000-00004 | DOI Listing |
Phys Rev Lett
December 2024
University of Oregon, Department of Physics and Materials Science Institute, Eugene, Oregon 97403, USA.
We consider many-particle diffusion in one spatial dimension modeled as "random walks in a random environment." A shared short-range space-time random environment determines the jump distributions that drive the motion of the particles. We determine universal power laws for the environment's contribution to the variance of the extreme first passage time and extreme location.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Family Medicine, University of Michigan, Ann Arbor.
Importance: Cervical cancer screening is a crucial public health intervention, but screening disparities exist for women with physical disabilities (WWPD).
Objective: To explore the experiences of WWPD with both traditional speculum examination-based screening and at-home self-sampling for cervical cancer screening.
Design, Setting, And Participants: This qualitative study enrolled 56 WWPD to test self-sampling kits, provide feedback via a survey, and participate in a qualitative interview.
Electromagn Biol Med
January 2025
Department of Mathematics, University of Gour Banga, Malda, India.
In cardiovascular research, electromagnetic fields generated by Riga plates are utilized to study or manipulate blood flow dynamics, which is particularly crucial in developing treatments for conditions such as arterial plaque deposition and understanding blood behavior under varied flow conditions. This research predicts the flow patterns of blood enhanced with gold and maghemite nanoparticles (gold-maghemite/blood) in an electromagnetic microchannel influenced by Riga plates with a temperature gradient that decays exponentially, under sudden changes in pressure gradient. The flow modeling includes key physical influences like radiation heat emission and Darcy drag forces in porous media, with the flow mathematically represented through unsteady partial differential equations solved using the Laplace transform (LT) method.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
School of Materials Science and Physics, China University of Mining and Technology, Xuzhou, Jiangsu Province 221116, China.
Geometries and electronic structures of planar and quasi-planar boron clusters resemble those of aromatic hydrocarbons, providing opportunities for designing novel nonlinear optical materials. However, the nonlinear optical properties, optical-response mechanisms, and optimal optical-response geometries of boron clusters remain unclear. Accordingly, this study addresses these uncertainties.
View Article and Find Full Text PDFThe multidimensional model of perfectionism includes three dimensions: Self-oriented perfectionism (SOP), other-oriented perfectionism (OOP), and socially prescribed perfectionism (SPP). Although previous research has identified significant cross-sectional associations between perfectionism and sexual function, these studies predominantly focused on women without examining the links between the different dimensions of perfectionism and various indicators of sexual difficulties among both members of a couple. This study aimed to address this gap by examining the dyadic associations between perfectionism dimensions, sexual function, partner-focused sexual desire, and sexual distress, both cross-sectionally (T1) and longitudinally (T2) over one year.
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