A spontaneous bone tumour in the foreleg of a Syrian hamster was shown to be a chondroma; this is only the second report of such a tumour and the first described in detail.
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Treatment of spatial memory impairment in hamsters infected with West Nile virus using a humanized monoclonal antibody MGAWN1.
Antiviral Res
July 2011
Department of Biomedical Sciences, Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, USA.
In addition to functional disorders of paresis, paralysis, and cardiopulmonary complications, subsets of West Nile virus (WNV) patients may also experience neurocognitive deficits and memory disturbances. A previous hamster study has also demonstrated spatial memory impairment using the Morris water maze (MWM) paradigm. The discovery of an efficacious therapeutic antibody MGAWN1 from pre-clinical rodent studies raises the possibility of preventing or treating WNV-induced memory deficits.
View Article and Find Full Text PDFEffects of bedding material and running wheel surface on paw wounds in male and female Syrian hamsters.
Lab Anim
January 2009
Département de Biologie, Université de Moncton, Moncton, New Brunswick E1A 3E9, Canada.
The present study investigated the effects of bedding material (pine shavings versus beta chip) and running wheel surfaces (standard metal bars versus metal bars covered with a plastic mesh) on the occurrence of wounds on the paws of male and female Syrian (golden) hamsters, Mesocricetus auratus. Four groups of 10 males and 10 females were each assigned to one of the following treatments: pine/no mesh, pine/mesh, chips/no mesh and chips/mesh. Each hamster paw was observed at 1-3-day intervals for 60 days.
View Article and Find Full Text PDFMalignant peripheral nerve sheath tumor in a hamster.
J Am Assoc Lab Anim Sci
November 2007
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
An adult female golden hamster (Mesocricetus auratus) developed a firm subcutaneous mass on the lateral distal right forelimb that progressed to diffuse limb enlargement accompanied by extensive cutaneous ulceration and drainage and axillary lymph node metastasis. Touch imprint cytology revealed pleomorphic neoplastic mesenchymal cells. On histology, the invasive neoplasm merged with a large subcutaneous nerve and was composed of spindle cells with a high mitotic index, and lymph node metastasis was confirmed.
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EMBO Rep
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Robert Koch-Institut, Berlin, Germany.
Scrapie, bovine spongiform encephalopathy and chronic wasting disease are orally communicable, transmissible spongiform encephalopathies (TSEs). As zoonotic transmissions of TSE agents may pose a risk to human health, the identification of reservoirs for infectivity in animal tissues and their exclusion from human consumption has become a matter of great importance for consumer protection. In this study, a variety of muscles from hamsters that were orally challenged with scrapie was screened for the presence of a molecular marker for TSE infection, PrPSc (the pathological isoform of the prion protein PrP).
View Article and Find Full Text PDFEvidence for rodent-common and species-typical limb and digit use in eating, derived from a comparative analysis of ten rodent species.
Behav Brain Res
November 1998
Department of Psychology and Neuroscience, University of Lethbridge, Alberta, Canada.
Order Rodentia comprises a vast portion of mammalian species (1814 species), which occupy extremely diverse habitats requiring very distinct motor specializations (e.g. burrowing, hopping, climbing, flying and swimming).
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