Objectives: To characterize the dementia associated with adult polyglucosan body disease (APBD) and to correlate the cognitive deficits with abnormalities found on magnetic resonance imaging (MRI).

Methods: Quantitative neuropsychological testing and MRI in one man with APBD and a review of the literature.

Results: The dementia of APBD affects cortical and subcortical functions. The cognitive deficits correlate with MRI findings of cortical atrophy and white-matter abnormalities.

Conclusion: Neuropsychological testing and MRI are helpful in the evaluation of patients with APBD.

Download full-text PDF

Source
http://dx.doi.org/10.1001/archneur.1994.00540130124021DOI Listing

Publication Analysis

Top Keywords

adult polyglucosan
8
polyglucosan body
8
body disease
8
cortical subcortical
8
cognitive deficits
8
neuropsychological testing
8
testing mri
8
dementia adult
4
disease evidence
4
evidence cortical
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!