The aim of the study is to assess the value of function tests of the autonomic nervous system in open-angle glaucoma by testing the cardiovascular reflexes and pupil cycle time. The experimental group consisted of 19 glaucoma subjects with controlled intraocular pressure. The control group consisted of 20 healthy volunteers. The Valsalva test has proven to be considerably accurate in the assertion of autonomic dysfunction (p < 0.05). Pupil cycle time was significantly prolonged (p < 0.001). These results confirm the role of autonomic dysfunction in open-angle glaucoma.
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http://dx.doi.org/10.1159/000310383 | DOI Listing |
Sci Rep
December 2024
School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, China.
Microtextured microneedles are tiny needle-like structures with micron-scale microtextures, and the drugs stored in the microtextures can be released after entering the skin to achieve the effect of precise drug delivery. In this study, the skin substitution model of Ogden's hyperelastic model and the microneedle array and microtexture models with different geometrical parameters were selected to simulate and analyse the flow of the microtexture microneedle arrays penetrating the skin by the finite-element method, and the length of the microneedles was determined to be 200 μm, the width 160 μm, and the value of the gaps was determined to be 420 μm. A four-pronged cone was chosen as the shape of microneedles, and a rectangle was chosen as the shape of the drug-carrying microneedle.
View Article and Find Full Text PDFEur J Ophthalmol
November 2024
Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain.
Purpose: To evaluate the clinical outcomes of a refractive multi-segmented continuous transitional focus intraocular lens (IOL), analyzing the potential influence of patient pupil dynamics on these outcomes.
Methods: Retrospective consecutive case series study enrolling 40 eyes (20 patients, 47-81 years) implanted with the Precizon Presbyopic IOL (Ophtec BV). The following clinical outcomes were analyzed during a mean follow-up of 12.
Micromachines (Basel)
September 2024
Department of Optics and Photonics, National Central University, Chungli 32001, Taiwan.
A projection lens with a 30-degree field of view is developed for use in augmented reality (AR) glasses, including a waveguide combiner designed for a 0.35-inch LCoS panel. The entrance pupil diameter of the lens is 14 mm and the lens has an effective focal length of 16.
View Article and Find Full Text PDFAdv Exp Med Biol
October 2024
School of Information Science and Technology, Nantong University, Nantong, Jiangsu Province, China.
This study aimed to investigate the effects of exercise on pupil dynamics, prefrontal haemodynamic, and salivary alpha-amylase (sAA) responses in 45 healthy graduate students. These participants were divided into two groups: a resting control group (CTL) and a very-light-intensity exercise group (EX). Participants in the EX-group engaged in a 10-min exercise at 30% O peak on a cycle ergometer.
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