The author demonstrated the transmission of chromosomal genes, controlling the histidine, proline, tryptophane synthesis, from Ps. aeruginosa to E. coli in conjugation mediated through the factor of drug resistance. A simultaneous transmission of the drug resistance and of the chromosomal genes by some transconjugants with further conjugation and also in transduction, a simultaneous transmission of the mentioned signs by transductants in conjugation with RecA--recipients, and also the presence of the satellite DNA peaks in the transconjugants permitted to draw a conclusion on the formation of the replaced RP factors, R'-his, R'-pro, and also R'-protrp.

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