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Lignin Metabolism Is Crucial in the Plant Responses to (Shen) in L.
Plants (Basel)
January 2025
Key Laboratory of Tea Quality and Safety Control, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.
(Shen) (Hemiptera: Cicadellidae) is a devastating insect pest species of , significantly affecting the yield and quality of tea. Due to growing concerns over the irrational use of insecticides and associated food safety, it is crucial to better understand the innate resistance mechanism of tea trees to . This study aims to explore the responses of tea trees to different levels of infestation.
View Article and Find Full Text PDFInterspecific Competition Between Riley and Hirst (Acari: Tetranychidae).
Insects
January 2025
Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
has long been recognized as an important spider mite pest of rubber trees. Recently, increasing damage from has elevated its importance as a key spider mite pest. These two species share highly overlapping ecological niches, with outbreaks strongly associated with high temperatures and drought stresses.
View Article and Find Full Text PDFNrf2 Regulates Basal Glutathione Production in Astrocytes.
Int J Mol Sci
January 2025
Program in Neuroscience, Department of Biology, Syracuse University, Syracuse, NY 13210, USA.
Astrocytes produce and export glutathione (GSH), an important thiol antioxidant essential for protecting neural cells from oxidative stress and maintaining optimal brain health. While it has been established that oxidative stress increases GSH production in astrocytes, with Nrf2 acting as a critical transcription factor regulating key components of the GSH synthetic pathway, the role of Nrf2 in controlling constitutive GSH synthetic and release mechanisms remains incompletely investigated. Our data show that naïve primary mouse astrocytes cultured from the cerebral cortices of Nrf2 knockout (Nrf2) pups have significantly less intracellular and extracellular GSH levels when compared to astrocytes cultured from Nrf2 wild-type (Nrf2) pups.
View Article and Find Full Text PDFAmygdala Nuclei Atrophy in Cognitive Impairment and Dementia: Insights from High-Resolution Magnetic Resonance Imaging.
Medicina (Kaunas)
January 2025
Institute of Public Health, Riga Stradins University, LV-1007 Riga, Latvia.
Cognitive impairment affects memory, reasoning, and problem-solving, with early detection being critical for effective management. The amygdala, a key structure in emotional processing and memory, may play a pivotal role in detecting cognitive decline. This study examines differences in amygdala nuclei volumes in patients with varying levels of cognitive performance to evaluate its potential as a biomarker.
View Article and Find Full Text PDFActivation of Genes by Nuclear Receptor/Specificity Protein (Sp) Interactions in Cancer.
Cancers (Basel)
January 2025
Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843, USA.
The human nuclear receptor (NR) superfamily consists of 48 genes that are ligand-activated transcription factors that play a key role in maintaining cellular homeostasis and in pathophysiology. NRs are important drug targets for both cancer and non-cancer endpoints as ligands for these receptors can act as agonists, antagonists or inverse agonists to modulate gene expression. With two exceptions, the classical mechanism of action of NRs involves their interactions as monomers, dimers or heterodimers with their cognate response elements (cis-elements) in target gene promoters.
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