Therapeutic effects of GnRH or its analogs have been tested in various physiological and pathological situations in domestic ruminants. Without any previous selection based on clinical observations, these treatments have a low efficiency to improve reproductive parameters. When used to induce ovulation in anoestrous females, GnRH or its analogs are less efficient than progestagen treatments associated with PMSG. On the contrary, GnRH can be used in females bearing follicular cysts or for the treatment of repeat breeders. Association of GnRH or its analogs to superovulation treatments is a new field of investigation. Additional experiments are necessary to show if it is possible to improve the response of superovulated females with such treatments.
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