Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Epigenome-wide association study of Chinese monozygotic twins identifies DNA methylation loci associated with estimated glomerular filtration rate.
J Transl Med
January 2025
Department of Epidemiology and Health Statistics, The School of Public Health of Qingdao University, 308 Ningxia Road, Qingdao, 266071, Shandong, People's Republic of China.
Background: DNA methylation (DNAm) has been shown in multiple studies to be associated with the estimated glomerular filtration rate (eGFR). However, studies focusing on Chinese populations are lacking. We conducted an epigenome-wide association study to investigate the association between DNAm and eGFR in Chinese monozygotic twins.
View Article and Find Full Text PDFThe mechanism of enterogenous toxin methylmalonic acid aggravating calcium-phosphorus metabolic disorder in uremic rats by regulating the Wnt/β-catenin pathway.
Mol Med
January 2025
Department of Nephrology, The Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Lianchi District, Baoding, 071000, Hebei Province, China.
Background: Uremia (UR) is caused by increased UR-related toxins in the bloodstream. We explored the mechanism of enterogenous toxin methylmalonic acid (MMA) in calcium-phosphorus metabolic disorder in UR rats via the Wnt/β-catenin pathway.
Methods: The UR rat model was established by 5/6 nephrectomy.
Long-term Metabolic Outcomes Post-Simultaneous Pancreas-Kidney Transplantation in Recipients With Type 1 Diabetes.
Transplantation
January 2025
Faculty of Medicine and Health, University of Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Background: Simultaneous pancreas-kidney (SPK) transplantation is an effective treatment option for type 1 diabetes mellitus and concurrent end-stage kidney disease. However, the diabetogenic effects of immunosuppression can counteract the beneficial effects of sustained normoglycemia. Long-term metabolic trends that reflect cardiovascular risk are reported poorly in the literature.
View Article and Find Full Text PDFThe rotation method for correcting renal depth in the determination of glomerular filtration rate using Tc-99m diethylenetriamine pentaacetic acid (DTPA)-based renal dynamic imaging in patients with hydronephrosis.
Quant Imaging Med Surg
January 2025
Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, China.
Background: Kidney depth significantly affects the accuracy of glomerular filtration rate (GFR) measurement, and hydronephrosis-induced morphological changes further challenge its estimation through traditional formulas. This study evaluated the rotation method's efficacy in correcting kidney depth and depth difference during Tc-99m diethylenetriamine pentaacetic acid (DTPA) renal dynamic imaging for GFR assessment.
Methods: This study analyzed 66 individuals treated at First Hospital of Shanxi Medical University with unilateral hydronephrosis between January 2022 and June 2023.
Performance of Glomerular Filtration Rate Estimating Equations in Kidney Transplant Recipients of Various Races: A Retrospective Cohort Study.
Transplant Proc
January 2025
Division of Medicine, Mayo Clinic Arizona, Phoenix, Arizona.
Background: We assessed the accuracy of different GFR estimating equations in kidney transplant recipients across diverse racial backgrounds, addressing the previously identified validation gap in multiethnic populations predominantly studied in White cohorts.
Methods: In this single-center study, eGFR was compared to the measured GFR (mGFR) one year following kidney transplantation.
Results: The 1-year eGFR and mGFR data from 1145 participants (54% Whites, 23% Hispanics, 9% Blacks, 7% Native Americans, and 6% Asians) revealed varied correlations across racial groups.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!