The author describes the methods for experimental study of the area around a traumatic skin wound, which up to now have been neglected by the hospital doctors and the investigators. The choice of the experimental animals and the methods for the preliminary preparatory work with them have been described. The author in details specifies the ways of injuring the skin--by thermal burn, mechanical crushing and combination of both, chemical injury and incision wound. All the manipulations of wounds are treated in inhalation ether anaesthesia. The methods proposed ensures replications and makes the results precise and sure. This fact gives the opportunity for usage of the methods for assessment and analysis of medicinal preparations and other means for treatment of wounds. The methods was created and used in experiments with 1200 experimental animals.

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