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GC/MS Analysis and Protective Effects of L. Essential Oil Against Antituberculosis Drug-Induced Organs Toxicity in Wistar Albino Rats.
Plants (Basel)
November 2024
Biology Department, College of Science, Taibah University, Al-Madinah Al-Munawara 42353, Saudi Arabia.
(L.) L., also known as wild mint, is a perennial herbaceous plant that belongs to the Lamiaceae family.
View Article and Find Full Text PDFNephroprotective and hepatoprotective effects of lemongrass essential oil and citral on diclofenac-induced toxicity in mice.
Biomed Pharmacother
November 2024
Department of Veterinary Medicine, University of Bari, 70010 Valenzano, Bari, Italy. Electronic address:
The present study was carried out to evaluate and compare the protective potential of two well-known antioxidants of herbal origin in a mouse model of acute DIC-induced nephro- and hepatotoxicity. The tested antioxidants included lemongrass essential oil (LO) and its predominant bioactive constituent citral (CIT). A third herbal product, silymarin (SILY), was used as a reference hepato-renal protective agent.
View Article and Find Full Text PDFArtemisia Argyi essential oil ameliorates acetaminophen-induced hepatotoxicity via CYP2E1 and γ-glutamyl cycle reprogramming.
Phytomedicine
December 2024
Henan Key Laboratory of Rehabilitation Medicine, Henan Joint International Research Laboratory of Chronic Liver Injury, Henan Workshop of Chronic Liver Injury for Outstanding Overseas Scientists, Zhengzhou Key Laboratory of Metabolic-dysfunction-associated Fatty Liver Disease, Department of Pharmacy, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China. Electronic address:
Article Synopsis
- - The study investigates the protective effects of Artemisia argyi essential oil (AAEO) against liver damage caused by acetaminophen (APAP) in mice, as APAP is known to induce hepatotoxicity.
- - Through various methods, including liver enzyme analysis and metabolic profiling, researchers found that AAEO mitigates liver damage by enhancing antioxidant activity and regulating liver metabolism.
- - Results indicated that AAEO helps reduce harmful levels of APAP in the liver by promoting the synthesis of glutathione (GSH), which helps detoxify the liver and prevent further damage.
Essential Oil Components Incorporated Emulsion Hydrogels for Eradicating Dermatophytosis Caused by Pathogenic Fungi Trichophyton mentagrophytes and Microsporum canis.
Adv Healthc Mater
November 2024
Polymer Nanobiomaterials Research Laboratory, Smart Materials and Devices (SMAD) Division, Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, 575018, India.
Dermatophytosis is a prevalent fungal infection and public health burden, majorly caused by the attack of zoophilic fungi genera of Trichophyton and Microsporum. Among them, T. mentagrophytes and M.
View Article and Find Full Text PDFDoes drug-induced liver injury still occur after sevoflurane anesthesia? -A case report.
Anesth Pain Med (Seoul)
July 2024
Department of Anesthesia and Pain Medicine, Samsung Changwon Hospital, Changwon, Korea.
Article Synopsis
- - Post-anesthetic hepatic dysfunction can result from various factors such as liver oxygen deficiency, physical compression, viral infections, blood transfusions, preexisting liver issues, and the use of harmful drugs, necessitating careful diagnosis to exclude these causes.
- - In a reported case, a patient developed significant liver enzyme elevation and mild jaundice following surgery with sevoflurane anesthesia, despite having no prior liver issues and undergoing an uneventful procedure.
- - The findings suggest that volatile anesthetic drug-induced liver injury (VA-DILI) is rare but possible, highlighting the need for awareness of its potential association with halogenated anesthetics during surgery.
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