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"COVID-19 affected me greatly (sigh), imagine I'm being called a mother and yet I'm also a child": the effect of COVID-19 on fertility management practices among women in Nairobi and Kisumu cities, Kenya.
Front Glob Womens Health
February 2025
Social and Behavioral Sciences, University of California, San Francisco, CA, United States.
Background: The COVID-19 pandemic strained the provision of sexual and reproductive health services, including family planning, which were categorized as non-essential services at the peak of COVID-19 infection control in Kenya. We set out to assess the effect of COVID-19 on fertility management practices among Kenyan women in two cities to inform mitigation measures in future similar disruptions.
Methods: This was a qualitative study to describe the effect of the COVID-19 pandemic on women's fertility management practices from 61 in-depth interviews (IDIs) with women aged 15-45 years residing in Nairobi and Kisumu, Kenya, between February and May 2021.
Sleep and pregnancy are contentious bedfellows; sleep disorders and disturbances are associated with adverse pregnancy outcomes, although much is still unknown about this relationship. Sleep and pregnancy have been studied in many models, but most focus heavily on mammals. However, pregnancy is ubiquitous across the animal kingdom - a hallmark of convergent evolution; similarly sleep is a shared feature across diverse species.
View Article and Find Full Text PDFEvaluation of efficacy and fertility after nonradical surgical therapy (extra fascial hysterectomy or cone biopsy, with pelvic lymphadenectomy) for stage IA1, IA2, and IB1 cervical cancer (GOG-0278).
Gynecol Oncol
March 2025
Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY, United States of America. Electronic address:
Objective: To estimate the efficacy and perioperative morbidity of nonradical surgery (simple hysterectomy [SH] or cone biopsy [CB] plus pelvic lymphadenectomy [PLND] and to report pregnancy outcomes after CB.
Methods: Prospective international study with 3-year follow-up of patients with stage IA1 (lymphovascular space invasion-positive) to IB1 (≤2 cm) cervical cancer stratified by fertility preservation (CB) or none (SH) (both with PLND). Criteria included ≤10 mm stromal invasion and negative margins on loop electrosurgical excision procedure or CB.
Mitral Transcatheter Edge-to-Edge Repair in a Pregnant Woman: Procedure and Pregnancy Outcomes.
JACC Case Rep
March 2025
Department of Cardiology, Bichat Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; INSERM U 1148, Paris, France; University of Paris Cité, Paris, France.
Secondary mitral regurgitation (MR) associated with left ventricular dysfunction carries a high risk of acute heart failure during pregnancy because of associated hemodynamic changes. Mitral transcatheter edge-to-edge repair (TEER) is currently recommended for symptomatic patients with secondary MR; however, no evidence exists on the use of this therapy in pregnancy. We present a case of secondary MR in a pregnant woman with dilated cardiomyopathy.
View Article and Find Full Text PDFAtosiban versus placebo for threatened preterm birth (APOSTEL 8): a multicentre, randomised controlled trial.
Lancet
March 2025
Department of Obstetrics and Gynaecology, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands; Amsterdam Reproduction and Development Research Institute, Amsterdam, Netherlands; Department of Obstetrics and Gynaecology, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Background: Tocolytics are recommended in international guidelines as treatment for threatened preterm birth. Atosiban, an oxytocin receptor antagonist, is a registered tocolytic drug specifically indicated for the treatment of threatened preterm birth. Although tocolytics have been shown to delay birth, benefits on neonatal outcomes have not been demonstrated.
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