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Depressive Symptoms and Amyloid Pathology.
JAMA Psychiatry
January 2025
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Importance: Depressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association between depressive symptoms and amyloid pathology.
View Article and Find Full Text PDFA unique case of cutaneous tuberculosis of the scalp with extensive intracranial invasion from sub Saharan Africa.
Acta Neurol Belg
January 2025
Department of Internal Medicine, Neurology Team, Kilimanjaro Christian Medical Centre, 3010, Moshi, Tanzania.
Extrapulmonary tuberculosis can present with a large variety of mimics of other, treatable, disorders. We present a young man with advanced cranial disease responding to tuberculostatic treatment but posing significant diagnostic and therapeutic challenges.
View Article and Find Full Text PDFNovel pain management strategy for uterine fibroid embolization.
CVIR Endovasc
January 2025
Department of Medical Imaging, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Background: Uterine fibroid embolization can be associated with significant pain due to fibroid ischemia and interventions of the procedure itself. Fentanyl and midazolam are commonly provided for sedation and pain relief, but are not tolerated by all patients. This report outlines a novel pain management strategy for uterine fibroid embolization in a patient who could not receive either opioids or benzodiazepines.
View Article and Find Full Text PDFStandard observation plane annotation for diagnosis of ossicular chain in the temporal bone CT images.
Med Biol Eng Comput
January 2025
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Temporal bone CT is an essential technique for diagnosing ossicular chain trauma, and the location of standard observation planes (SOP) is the foundation of imaging diagnosis. The ossicular chain is small in volume, and there are about 11 standard observation planes for ossicular chain diagnosis, so it is a professional and time-consuming task to label SOPs accurately. An automatic annotation method of SOP is proposed.
View Article and Find Full Text PDFPrimary diffuse leptomeningeal atypical teratoid/rhabdoid tumours (ATRT) of childhood: a molecularly characterised case report and literature review.
Childs Nerv Syst
January 2025
The Geoffrey Jefferson Brain Research Centre, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Background: Atypical teratoid/rhabdoid tumours (ATRTs) are malignant central nervous system tumours, typically presenting in the posterior fossa of very young children. Prognosis remains poor despite current therapy, while tumorigenesis implicates both genomic and epigenetic dysregulation. Primary diffuse leptomeningeal (PDL) ATRT, characterised by the absence of an intraparenchymal mass lesion, is seldom reported but appears associated with a dismal outcome.
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