AI Article Synopsis
- Two patients presented with chronic lipoatrophic panniculitis, leading to significant skin damage and loss of fat tissue.
- Histological examination revealed mixed septal and lobular panniculitis with evidence of lipophagia, indicating a specific diagnosis.
- The first patient improved with antimalarial treatment, enabling subsequent reconstructive surgery to address the disfigurement.
Article Abstract
Two patients with widespread, chronic, relapsing panniculitis resulting in disfiguring lipoatrophy are reported. Histology in both cases showed a mixed septal and lobular panniculitis, with lipophagia. The clinical appearance and histology suggested a diagnosis of lipoatrophic panniculitis. Both cases had features of connective tissue panniculitis, which is likely to be a subtype of this condition. Treatment of lipoatrophic panniculitis can be difficult. Our first patient initially responded well to antimalarial therapy, allowing plastic surgical repair of the defects to be carried out.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1365-2133.1993.tb00498.x | DOI Listing |
Publication Analysis
Top Keywords
lipoatrophic panniculitis
12
connective tissue
8
tissue panniculitis
8
panniculitis
7
clinical spectrum
4
spectrum lipoatrophic
4
panniculitis encompasses
4
encompasses connective
4
panniculitis patients
4
patients widespread
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!