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Continuous risk monitoring and management of heart failure: Rationale and design of the ALLEVIATE-HF trial.
Eur J Heart Fail
January 2025
Medical University of South Carolina, Charleston, SC, USA.
Aims: Early identification and management of worsening heart failure (HF) is necessary to prevent disease progression and hospitalizations. The ALLEVIATE-HF (Algorithm Using LINQ Sensors for Evaluation and Treatment of Heart Failure) trial is a prospective, randomized, controlled, double-blind, multicentre trial that aims to assess the safety and efficacy of using the Reveal LINQ™ insertable cardiac monitor (ICM) in patients with HF to continuously monitor and evaluate HF risk status and guide timely interventions.
Methods: The ICM algorithm uses parameters derived from electrocardiogram (atrial fibrillation [AF], ventricular rate during AF, heart rate variability, and night heart rate), three-axis accelerometer (patient activity duration), and subcutaneous bioimpedance (fluid volume, respiration rate).
The action of retinoic acid on spermatogonia in the testis.
Curr Top Dev Biol
January 2025
School of Molecular Biosciences, Washington State University, Pullman, Washington, United States. Electronic address:
For mammalian spermatogenesis to proceed normally, it is essential that the population of testicular progenitor cells, A undifferentiated spermatogonia (A), undergoes differentiation during the A to A1 transition that occurs at the onset of spermatogenesis. The commitment of the A population to differentiation and leaving a quiescent, stem-like state gives rise to all the spermatozoa produced across the lifespan of an individual, and ultimately determines male fertility. The action of all-trans retinoic acid (atRA) on the A population is the determining factor that induces this change.
View Article and Find Full Text PDFObjective: Obesity is a disease with severe health impacts on individuals and economic impacts on society, yet healthcare practitioners (HCPs) and policy makers often fail to address it. This survey was conducted to examine current global obesity care and perceptions influencing care delivery among HCPs and healthcare decision makers (HC DMs).
Methods: A survey with a cross-sectional design was conducted among 1200 HCPs (primary care providers, endocrinologists, cardiologists, and nurses) and 414 HC DMs from eight countries across five continents.
An exploratory study of nursing tasks that induce physical and mental stress among hospital nurses.
Appl Nurs Res
December 2024
College of Nursing, The Graduate school, Ewha Womans University, Seoul, Republic of Korea. Electronic address:
Background: Nursing tasks are major contributing factors of nurses' stress. Identifying these stress-inducing tasks by hospital and department is the first step in devising practical strategies to address this issue.
Objectives: This study aimed to develop a nursing task list by categorizing nursing tasks and identifying the ones that induced physical and mental stress among hospital nurses.
The Impact of Technostress, Nursing Informatics Competency and Knowledge-Sharing Behaviour on Nursing Work Performance Among Tertiary Hospital Nurses.
J Adv Nurs
November 2024
College of Nursing, Keimyung University, Deagu, South Korea.
Aims: To examine the impact of technostress, nursing informatics competency and knowledge-sharing behaviour on clinical nurses' work performance.
Design: A cross-sectional study.
Method: We recruited nurses with over 6 months of experience from three tertiary hospitals in Daegu, Korea.
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