The preferred form of acute bronchodilator therapy is to administer aerosolized beta-agonist by a metered-dose inhaler. Many patients cannot use this device efficiently, the major problem being coordination of dose release with inspiration. A new breath-actuated inhaler (the Autohaler actuator) has been developed to overcome this problem. The objective of this study was to evaluate patient's and staff's perceptions of this device. Ninety-eight percent of patients rated the device easy to use and 83% rated the overall use as excellent or good. The staffs rated it as excellent or good for 93% of patients. It was concluded that patients would accept this device, and greater patient compliance could be realized.
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http://dx.doi.org/10.3109/02770909309056752 | DOI Listing |
J Aerosol Med Pulm Drug Deliv
October 2017
2 Mundipharma Research Limited , Cambridge, United Kingdom .
Background: Fluticasone propionate/formoterol (FP/FORM) is a pressurized metered-dose inhaler (pMDI; Flutiform) approved for use in adolescents and adults and under development for pediatric use.
Objective: To compare short-term growth in asthmatic children treated with FP/FORM, FP pMDI with valved holding chamber, and beclomethasone dipropionate (BDP) in a breath-actuated device.
Methods: Children with persistent asthma (n = 48; 5 to <12 years) participated in an assessor-blinded, randomized, three-way crossover trial with run in, wash out, and active treatment periods, each of 2 weeks duration.
Respir Med
December 2011
Service de Pneumologie, Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris, France.
Poor inhaler technique is frequent in asthma, but its long-term consequences have been seldom assessed. Pharmacists are ideally positioned to teach inhaler technique. This prospective observational study evaluated the feasibility of inhaler training by pharmacists in patients receiving inhaled corticosteroids by pressurised metered-dose inhaler (pMDI) or breath-actuated MDI.
View Article and Find Full Text PDFEur Rev Med Pharmacol Sci
May 2011
TEVA Santé, Paris La Défense, France.
Background: Asthma guidelines recommend that patients receive inhaler technique training, with rechecks at each visit. However, suboptimal inhaler technique is common.
Methods: This prospective observational study evaluated patient training in use of the Autohaler, a breath-actuated metered-dose inhaler.
Eur Rev Med Pharmacol Sci
January 2010
Teva Santé, Paris La Défense, France.
Background And Objectives: Poor inhalation technique may impact both asthma control and compliance in patients with asthma. The SYSTER survey is therefore aimed at assessing the influence of starting or switching an existing therapy to a breath-actuated pressurized metered dose inhaler (pMDI, Autohaler) on these parameters.
Materials And Methods: 709 French general practitioners (GP) enrolled 2588 asthmatic patients in whom therapy with the breath-actuated pMDI was either initiated, or a switch from an existing inhalation device to the said inhaler was deemed necessary.
Background: For inhalation as a mainstay of asthma therapy, the correct inhalation technique is of utmost importance. This comprises not only the correct handling of the device but also specific device-dependent requirements concerning the inhalation manoeuvre itself.
Methods: We examined whether totally different inhalation manoeuvres can be educated in parallel in asthmatic children.
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