The larvae of Baylisascaris transfuga (Rudolphi, 1819) were able to penetrate the liver, lungs, carcass and brain of infected chickens, but a great number of larvae accumulated in the liver. No clinical signs were seen. Birds may serve as paratenic hosts of the parasite, but B. transfuga seems not to be a possible agent of avian cerebrospinal nematodosis.
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Acta Parasitol
January 2025
Centralized Instrumentation Laboratory, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, 600 007, India.
Introduction: Toxocarosis in human beings is currently diagnosed by serological assay based on the detection of antibodies against Toxocara antigens. Toxocara canis larvae do not reach the adult stage in paratenic hosts like humans and mice. Therefore experimental infection in mice, which mimics the biology of human infection, might be relevant to get a better understanding of human toxocarosis.
View Article and Find Full Text PDFVet Parasitol Reg Stud Reports
January 2025
Department of Biomedical and Diagnostic Sciences, University of Tennessee College of Veterinary Medicine, 2407 River Dr., Knoxville, TN 37996, USA.
The ascarid nematode, Toxocara vitulorum, is a destructive parasite of ruminants with a world-wide distribution that causes mortality in calves, especially those with poor nutrition. Reports of T. vitulorum are scarce in the continental U.
View Article and Find Full Text PDFActa Parasitol
January 2025
Faculty of Veterinary Medicine, Department of Parasitology, Kirikkale University, Kirikkale, 71450, Türkiye.
Purpose: In the present study, the effects of leaf and rhizome extracts of Arum rupicola Boiss rupicola were searched on the infective stage Toxocara canis larvae (L3) in the experimentally infected mice.
Methods: Four-six week-old male BALB/c mice were divided into eight groups (G1-8, each group consisted of 7 mice), and they were infected orally with 500 T. canis eggs with L3.
Sci Rep
January 2025
Institute of Immunology, Centre of Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Soil-transmitted helminths (STH) are widespread, with Ascaris lumbricoides infecting millions globally. Malaria and STH co-infections are common in co-endemic regions. Artemisinin derivatives (ARTs)-artesunate, artemether, and dihydroartemisinin-are standard malaria treatments and are also known to influence the energy metabolism of parasites, tumors, and immune cells.
View Article and Find Full Text PDFVet Med Sci
January 2025
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.
Thiazoles serve as pharmacophores in many molecules that exhibit significant biological activity. This study used in vitro assays and in silico methodologies to identify novel medication candidates for preclinical evaluation of visceral toxocariasis treatment. The objective was to assess the impact of 11 thiazolohydrazone derivative compounds on the larval eggs of Toxocara canis.
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