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Herbicide glyphosate efficiently inhibits growth of pathogenic algae species, suggesting the presence of novel pathways for the development of anti-algal drugs.
Microbiol Spectr
January 2025
Institute for Animal Hygiene and Environmental Health, Freie Universität Berlin, Berlin, Germany.
are ubiquitous algae and occasional pathogens of humans and animals. While rare, the infection is often fatal and treatment options are limited to antifungals with low efficiency. Here, using growth curve assays, we demonstrate that five pathogenic species of () were fully inhibited by 50-100 μg/mL of herbicide glyphosate, suggesting novel pathways that can be considered for anti-algal drug development.
View Article and Find Full Text PDFEvaluation of the effect of dental caries, oral hygiene, and treatment need on oral health-related quality of life among Turkish orphan children and adolescents.
BMC Oral Health
January 2025
Department of Pediatric Dentistry, School of Dentistry, Marmara University, Istanbul, Türkiye.
Background: The oral and dental health and related quality of life of orphan children and adolescents-who are considered a vulnerable population-are critical for both individual and public health.
Objectives: This study aimed to investigate the status of the dental caries, oral hygiene, and dental treatment needs among a group of Turkish male orphan children and adolescents, as well as their impact on oral health-related quality of life.
Methods: A total of 112 orphan children and adolescents aged between 9 and 17 years living in a residential care facility in Istanbul, Türkiye, were involved in this cross-sectional study.
Reverse vaccinology: A strategy also used for identifying potential vaccine antigens in poultry.
Vaccine
January 2025
GVB-Viral Genetics and Biosafety Unit, French Agency for Food, Environmental and Occupational Health & Safety (ANSES), France; VIPAC-Avian and Rabbit Virology, Immunology and Parasitology Unit, French Agency for Food, Environmental and Occupational Health & Safety (ANSES), France. Electronic address:
Vaccination of livestock plays a major role in improving animal health, welfare and productivity, but also in public health by preventing zoonotic diseases. Advances in bioinformatics and whole-genome sequencing techniques since the 2000s have led to the development of genome-based vaccinology, called reverse vaccinology. Reverse vaccinology is a rapid and competitive strategy that uses pathogen genome sequences to screen for and identify potential vaccine antigens and, unlike conventional methods, does not require culturing the pathogenic microorganism, at least initially.
View Article and Find Full Text PDFDefining Health Management: A Conceptual Foundation for Excellence Through Efficiency, Sustainability and Equity.
Int J Health Plann Manage
January 2025
European Health Management Association, Brussels, Belgium.
The practice of healthcare management is essential for the efficient operation of health services, encompassing leadership, management, and direction within healthcare organisations. 'Health management' extends beyond healthcare management by integrating principles of public health and health policy. As health management is commonly practised but not cohesively recognised, the European Health Management Association (EHMA) conducted this study to develop a cohesive definition of health management.
View Article and Find Full Text PDFGreen Dentistry: State of the Art and Possible Development Proposals.
Dent J (Basel)
January 2025
Chair Center for Oral Hygiene and Prevention, Department of Dentistry, Dental School, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, 20132 Milan, Italy.
: The objective of this narrative literature review was to highlight all dental procedures attributable to sectoral waste and to consider possible alternatives in line with the concept of sustainable development. : An extensive search of electronic databases, including the Cochrane Oral Health Group Specialized Register, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, PubMed, EMBASE, and Google Scholar. Search words included 'Green Dentistry', 'Dental Pollution', 'Pollutants and Dentistry', 'Disinfectants and Dentistry', and 'High-tech Dentistry'.
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