Nitrofurantoin is used in the treatment of, and to prevent, urinary tract infections. Since this chemotherapeutic agent was introduced in the fifties, quite a number of cases of acute and chronic pulmonary damage have been reported that were conditioned by nitrofurantoin. This is a report on three cases of pulmonary nitrofurantoin reactions, one of them acute and two chronic. All three patients were examined with the inclusion of bronchoalveolar lavage and transbronchial lung biopsy. In all three cases alveolitides of varying activity were confirmed. The radiological and CT findings are described.

Download full-text PDF

Source

Publication Analysis

Top Keywords

acute chronic
8
three cases
8
[pulmonary toxicity
4
toxicity caused
4
caused nitrofurantoin]
4
nitrofurantoin] nitrofurantoin
4
nitrofurantoin treatment
4
treatment prevent
4
prevent urinary
4
urinary tract
4

Similar Publications

Nasal high flow (NHF) therapy is an established form of non invasive respiratory support used in acute and chronic care. Recently, a new high flow nasal cannula with asymmetric prongs was approved for clinical use. The clinical benefits of the new cannula have not yet been defined and no evidence are available on the use of asymmetric NHF support in patient with Chronic Obstructive Pulmonary Disease (COPD).

View Article and Find Full Text PDF

Importance: Rising prescription medication costs under Medicaid have led to increased procedural prescription denials by health plans. The effect of unresolved denials on chronic condition exacerbation and subsequent acute care utilization remains unclear.

Objective: To examine whether procedural prescription denials are associated with increased net spending through downstream acute care utilization among Medicaid patients not obtaining prescribed medication following a denial.

View Article and Find Full Text PDF

This study examined internal, external training loads, internal:external ratios, and aerobic adaptations for acute and short-term chronic repeated-sprint training (RST) with blood flow restriction (BFR). Using randomised crossover (Experiment A) and between-subject (Experiment B) designs, 15 and 24 semi-professional Australian footballers completed two and nine RST sessions, respectively. Sessions comprised three sets of 5-7 × 5-second sprints and 25 seconds recovery, with continuous BFR (45% arterial occlusion pressure) or without (Non-BFR).

View Article and Find Full Text PDF

Background: In an Italian cohort of lupus podocytopathy patients, we aimed to characterize the presenting features, therapy, and outcomes, and explore differences between relapsing and non-relapsing patients.

Methods: We identified 29 patients with lupus podocytopathy from 1994 to 2023 in 11 Italian Nephrology/Rheumatology Units, and divided them into two groups: relapsing and non-relapsing. Given the limited sample size, a p-value ≤ 0.

View Article and Find Full Text PDF

Effects of engineered nanomaterials on the cardiovascular system.

J Occup Health

January 2025

Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke 329-0498Japan.

With the explosive development of nanotechnology, engineered nanomaterials are currently being used in various industries, including food and medicine. Concern about the health effects of nanomaterials has been raised, and available research indicates that the relative surface area of nanomaterials seems to correlate with the severity of their toxicity. With regard to engineered nanomaterials, the scope of their acute and chronic toxicities and their mechanisms are not fully understood.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!